T. Rowe Price Exchange-Traded Funds Inc.

02/23/2026 | Press release | Distributed by Public on 02/23/2026 10:31

Annual Report by Investment Company (Form N-CSR)

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM N-CSR

CERTIFIED SHAREHOLDER REPORT OF REGISTERED

MANAGEMENT INVESTMENT COMPANIES

Investment Company Act File Number: 811-23494

T. Rowe Price Exchange-Traded Funds, Inc.

(Exact name of registrant as specified in charter)

1307 Point Street, Baltimore, MD 21231

(Address of principal executive offices)

David Oestreicher

1307 Point Street, Baltimore, MD 21231

(Name and address of agent for service)

Registrant's telephone number, including area code: (410) 345-2000

Date of fiscal year end: December 31

Date of reporting period: December 31, 2025

Item 1. Reports to Shareholders

(a) Report pursuant to Rule 30e-1

Annual Shareholder Report

December 31, 2025

Health Care ETF (TMED)

Principal Listing Exchange: Nasdaq Stock Market LLC

This annual shareholder report contains important information about Health Care ETF (the "fund") for the period of June 11, 2025 to December 31, 2025. You can find the fund's prospectus, financial information on Form N-CSR (which includes required tax information for dividends), holdings, proxy voting information, and other information at www.troweprice.com/prospectus. You can also request this information without charge by contacting T. Rowe Price at 1-800-638-5660 or [email protected]or by contacting your intermediary.

What were the fund costs for the last year?(based on a hypothetical $10,000 investment)

Fund name
Costs of a $10,000 investment
Costs paid as a percentage of a $10,000 investment
Health Care ETF
$27
0.44%

What drove fund performance during the past period?

  • Health care stocks advanced, overcoming challenges including regulatory/policy headwinds and elevated health care utilization rates. Notable gains in the fourth quarter stemmed from factors such as a series of positive clinical datasets in large indications, robust product launches, and heightened merger and acquisition activity. Additionally, the outlooks for a broad swath of pharmaceutical companies improved due to increased clarity on U.S. drug pricing reform.

  • Relative to the S&P Health Care Select Sector Index, the top-performing sector for the since-inception period, by a large margin, was biotechnology. Within that sector, Cytokinetics, also a top absolute contributor, benefited from positive clinical trial data for its flagship drug, aficamten. The largest absolute contributor overall was pharmaceutical company Eli Lilly, supported by outperformance in its GLP-1 franchise.

  • Conversely, the leading detractor from relative results was the life sciences tools and services sector. Our holdings here delivered strong returns but lagged the benchmark. From an absolute perspective, the largest detractor was managed care company Elevance Health. The company's lowered profit outlook amid higher medical cost trends weighed on the stock price. Shares of global health care company Abbot Laboratories also finished lower as weakness in its diagnostics segment hampered forward guidance.

  • Our approach focuses on finding innovative companies that have the greatest ability to bring cutting-edge products and high-impact treatments to the health care marketplace that will change the practice of medicine and satisfy unmet clinical needs.

How has the fund performed?

Cumulative Returns of a Hypothetical $10,000 Investment as of December 31, 2025

ETF (Based on Net Asset Value)
Regulatory Benchmark
Strategy Benchmark
6/11/25
9,924
10,240
9,979
9/2025
10,664
11,021
10,355
12/2025
11,936
11,384
11,564

202505-4541202, 202601-5112365

ETF1194-052 02/26

Average Annual Total Returns

Fund
Since Inception 6/11/25
Health Care ETF (Based on Net Asset Value)
19.36%
MSCI All Country World Index Net (Regulatory Benchmark)
13.84%
S&P Health Care Select Sector Index (Strategy Benchmark)
15.64%

The preceding line graph shows the value of a hypothetical $10,000 investment in the fund over the past 10 fiscal year periods or since inception (for funds lacking 10-year records). The fund's performance information included in the line graph and table above is compared with a regulatory required index that represents an overall securities market (Regulatory Benchmark). In addition, the line graph and table may also include one or more indexes that more closely aligns to the fund's investment strategy (Strategy Benchmark(s)). The fund's total return figures reflect the reinvestment of dividends and capital gains, if any. Neither the fund's returns nor the index returns reflect the deduction of taxes that a shareholder would pay on fund distributions or redemptions of fund shares. The fund's past performance is not a good predictor of the fund's future performance.Updated performance information can be found at www.troweprice.com.

What are some fund statistics?

Fund Statistics

  • Total Net Assets (000s)$16,323
  • Number of Portfolio Holdings107
  • Investment Advisory Fees Paid (000s)$32
  • Portfolio Turnover Rate44.0%

What did the fund invest in?

Industry Allocation (as a % of Net Assets)

Biotechnology
31.1%
Health Care Equipment & Supplies
21.8
Pharmaceuticals
19.6
Health Care Providers & Services
14.4
Life Sciences Tools & Services
12.8
Health Care Technology
0.1
Other
0.2

Top Ten Holdings (as a % of Net Assets)

Eli Lilly
14.8%
UnitedHealth Group
7.3
Abbott Laboratories
4.6
Gilead Sciences
3.9
Intuitive Surgical
3.7
AbbVie
3.7
Thermo Fisher Scientific
3.7
Danaher
3.1
Becton Dickinson & Company
2.6
Cytokinetics
2.5

If you invest directly with T. Rowe Price, you can elect to receive future shareholder reports or other important documents through electronic delivery by enrolling at www.troweprice.com/paperless. If you invest through a financial intermediary such as an investment advisor, a bank, retirement plan sponsor or a brokerage firm, please contact that organization and ask if it can provide electronic delivery.

MSCI and S&P do not accept any liability for any errors or omissions in the indexes or data, and hereby expressly disclaim all warrantiesof originality, accuracy, completeness, timeliness, merchantability and fitness for a particular purpose. No party may rely on any indexes or data contained in thiscommunication. Visit www.troweprice.com/en/us/market-data-disclosuresfor additional legal notices & disclaimers.

Health Care ETF (TMED)

T. Rowe Price Investment Services, Inc.

1307 Point Street

Baltimore, Maryland 21231

Principal Listing Exchange: Nasdaq Stock Market LLC

Item 1. (b) Notice pursuant to Rule 30e-3.

Not applicable.

Item 2. Code of Ethics.

The registrant has adopted a code of ethics, as defined in Item 2 of Form N-CSR,applicable to its principal executive officer, principal financial officer, principal accounting officer or controller, or persons performing similar functions. A copy of this code of ethics is filed as an exhibit to this Form N-CSR.No substantive amendments were approved or waivers were granted to this code of ethics during the period covered by this report.

Item 3. Audit Committee Financial Expert.

The registrant's Board of Directors has determined that Mr. Paul F. McBride qualifies as an audit committee financial expert, as defined in Item 3 of Form N-CSR.Mr. McBride is considered independent for purposes of Item 3 of Form N-CSR.

Item 4. Principal Accountant Fees and Services.

(a) - (d) Aggregate fees billed for the last two fiscal years for professional services rendered to, or on behalf of, the registrant by the registrant's principal accountant were as follows:

    2025 2024

Audit Fees

$ 26,147 $-

Audit-Related Fees

- -

Tax Fees

- -

All Other Fees

- -

Audit fees include amounts related to the audit of the registrant's annual financial statements and services normally provided by the accountant in connection with statutory and regulatory filings. Audit-related fees include amounts reasonably related to the performance of the audit of the registrant's financial statements and specifically include the issuance of a report on internal controls and, if applicable, agreed-upon procedures related to fund acquisitions. Tax fees include amounts related to services for tax compliance, tax planning, and tax advice. The nature of these services specifically includes the review of distribution calculations and the preparation of Federal, state, and excise tax returns. All other fees include the registrant's pro-ratashare of amounts for agreed-upon procedures in conjunction with service contract approvals by the registrant's Board of Directors/Trustees.

(e)(1) The registrant's audit committee has adopted a policy whereby audit and non-auditservices performed by the registrant's principal accountant for the registrant, its investment adviser, and any entity controlling, controlled by, or under common control with the investment adviser that provides ongoing services to the registrant require pre-approvalin advance at regularly scheduled audit committee meetings. If such a service is required between regularly scheduled audit committee meetings, pre-approvalmay be authorized by one audit committee member with ratification at the next scheduled audit committee meeting. Waiver of pre-approvalfor audit or non-auditservices requiring fees of a de minimis amount is not permitted.

  (2) No services included in (b) - (d) above were approved pursuant to paragraph (c)(7)(i)(C) of Rule 2-01of Regulation S-X.

(f) Less than 50 percent of the hours expended on the principal accountant's engagement to audit the registrant's financial statements for the most recent fiscal year were attributed to work performed by persons other than the principal accountant's full-time, permanent employees.

(g) The aggregate fees billed for the most recent fiscal year and the preceding fiscal year by the registrant's principal accountant for non-auditservices rendered to the registrant, its investment adviser, and any entity controlling, controlled by, or under common control with the investment adviser that provides ongoing services to the registrant were $1,862,000 and $1,262,000, respectively.

(h) All non-auditservices rendered in (g) above were pre-approvedby the registrant's audit committee. Accordingly, these services were considered by the registrant's audit committee in maintaining the principal accountant's independence.

(i) Not applicable.

(j) Not applicable.

Item 5. Audit Committee of Listed Registrants.

Not applicable.

Item 6. Investments.

(a) Not applicable. The complete schedule of investments is included in Item 7 of this Form N-CSR.

(b) Not applicable.

Item 7. Financial Statements and Financial Highlights for Open-EndManagement Investment Companies.

(a - b) Report pursuant to Regulation S-X.

Financial Statements and Other Information
December 31, 2025
T. ROWE PRICE
TMED Health Care ETF
For more insights from T. Rowe Price investment professionals, go totroweprice.com.
T. ROWE PRICE HEALTH CARE ETF
FINANCIAL HIGHLIGHTS
For a share outstanding throughout the period
6/11/25(1)
Through
12/31/25
NET ASSET VALUE
Beginning of period $ 25.00
Investment activities
Net investment income(2)(3) 0.10
Net realized and unrealized gain/loss 4.74
Total from investment activities 4.84
Distributions
Net investment income (0.16)
NET ASSET VALUE
End of period $ 29.68
Ratios/Supplemental Data
Total return, based on NAV(3)(4) 19.36%
Ratios to average net
assets:(3)
Gross expenses before
waivers/payments by
Price Associates
0.44%(5)
Net expenses after
waivers/payments by
Price Associates
0.44%(5)
Net investment income 0.63%(5)
Portfolio turnover rate(6) 44.0%
Net assets, end of period
(in thousands)
$ 16,323
(1) Inception date 
(2) Per share amounts calculated using average shares outstanding method. 
(3) Includes the impact of expense-related arrangements with Price Associates. 
(4) Total return reflects the rate that an investor would have earned on an investment in the fund during the period, assuming reinvestment of all distributions. Total return is not annualized for periods less than one year. 
(5) Annualized 
(6) Portfolio turnover excludes securities received or delivered through in-kind share transactions. 
The accompanying notes are an integral part of these financial statements.
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T. ROWE PRICE HEALTH CARE ETF
December 31, 2025
PORTFOLIO OF INVESTMENTS Shares $ Value
(Cost and value in $000s)
COMMON STOCKS 99.7%
HEALTH CARE 99.7%
Biotechnology 31.1%
89bio (1)(2) 2,477 -
AbbVie 2,652 606
Abivax, ADR (2) 452 61
Agios Pharmaceuticals (2) 892 24
Alkermes (2) 2,079 58
Apogee Therapeutics (2) 1,295 98
Applied Therapeutics (2) 153,622 15
Arcellx (2) 3,489 227
Arcus Biosciences (2) 1,974 50
Arcus Biosciences Inc (2) 1,625 39
Ascendis Pharma, ADR (2) 923 197
Avalo Therapeutics (2) 3,386 61
Bicara Therapeutics (2) 3,129 53
Biogen (2) 1,358 239
BioNTech, ADR (2) 1,686 160
Black Diamond Therapeutics (2) 13,151 32
Cabaletta Bio (2) 37,423 82
Caris Life Sciences (2) 2,097 57
Centessa Pharmaceuticals, ADR (2) 1,526 38
CG Oncology (2) 1,242 52
CRISPR Therapeutics (2) 1,034 54
Cytokinetics (2) 6,343 403
Denali Therapeutics (2) 4,723 78
Dyne Therapeutics (2) 11,549 226
Erasca (2) 24,274 90
Gilead Sciences 5,152 632
Immatics (2)(3) 14,885 156
Immucore Holdings, ADR (2) 2,047 71
2
T. ROWE PRICE HEALTH CARE ETF
Shares $ Value
(Cost and value in $000s)
Immunome (2) 6,409 138
Immunovant (2) 2,263 58
Incyte (2) 652 64
Ionis Pharmaceuticals (2) 1,342 106
Janux Therapeutics (2) 1,726 24
Jasper Therapeutics (2) 4,635 8
Jasper Therapeutics, Warrants, 3/22/30 (1)(2) 5,370 6
Karyopharm Therapeutics (2) 7,190 53
Karyopharm Therapeutics, Warrants, 10/3/28 (2) 3,159 11
Kodiak Sciences (2) 2,146 60
Kymera Therapeutics (2) 146 11
MapLight Therapeutics (2) 4,294 75
Metsera (1)(2) 1,892 -
Moderna (2) 980 29
MoonLake Immunotherapeutics (2)(3) 3,557 47
Nurix Therapeutics (2) 508 10
Prime Medicine (2) 11,459 40
Revolution Medicines (2) 212 17
Roivant Sciences (2) 1,982 43
Sarepta Therapeutics (2) 3,464 75
Shattuck Labs (2) 18,643 68
Soleno Therapeutics (2) 484 22
Summit Therapeutics (2) 1,873 33
Tango Therapeutics (2) 865 8
Vaxcyte (2) 3,203 148
Xenon Pharmaceuticals (2) 1,333 60
5,073
Health Care Equipment & Supplies 21.8%
Abbott Laboratories 6,024 755
Alcon 721 57
Align Technology (2) 394 61
Becton Dickinson & Company 2,189 425
Cooper (2) 2,120 174
3
T. ROWE PRICE HEALTH CARE ETF
Shares $ Value
(Cost and value in $000s)
Dexcom (2) 2,645 176
Edwards Lifesciences (2) 1,929 164
GE HealthCare Technologies 549 45
Insulet (2) 313 89
Intuitive Surgical (2) 1,079 611
Masimo (2) 439 57
Medkine, Class A (2) 1,045 44
Medtronic 3,112 299
Novocure (2) 3,143 41
Penumbra (2) 199 62
PROCEPT BioRobotics (2)(3) 901 28
Solventum (2) 511 40
Steris 232 59
Stryker 924 325
Ypsomed Holding (CHF) 120 49
3,561
Health Care Providers & Services 14.4%
Alignment Healthcare (2) 3,041 60
Billiontoone, Class A (2) 142 12
Cencora 801 270
CVS Health 3,034 241
GeneDx Holdings (2) 189 25
Humana 739 189
McKesson 215 176
Molina Healthcare (2) 890 154
Oscar Health, Class A (2) 2,484 36
UnitedHealth Group 3,611 1,192
2,355
Health Care Technology 0.1%
Schrodinger (2) 1,033 18
18
4
T. ROWE PRICE HEALTH CARE ETF
Shares $ Value
(Cost and value in $000s)
Life Sciences Tools & Services 12.7%
Adaptive Biotechnologies Corp (2) 3,128 51
Agilent Technologies 1,466 199
Bruker 1,439 68
Danaher 2,226 510
Mettler-Toledo International (2) 125 174
Repligen (2) 566 93
Stevanato Group 3,184 64
Thermo Fisher Scientific 1,039 602
Waters (2) 411 156
West Pharmaceutical Services 556 153
2,070
Pharmaceuticals 19.6%
Amylyx Pharmaceuticals (2) 4,156 50
AstraZeneca, ADR 694 64
ATAI Life Sciences (2) 3,070 13
Cybin (2) 1,469 12
Elanco Animal Health (2) 17,214 389
Eli Lilly 2,253 2,421
Novo Nordisk, ADR 802 41
Rapport Therapeutics (2) 1,821 55
Sanofi, ADR 3,108 151
3,196
Total Health Care 16,273
Total Common Stocks (Cost $15,067) 16,273
5
T. ROWE PRICE HEALTH CARE ETF
Shares $ Value
(Cost and value in $000s)
PREFERRED STOCKS 0.1%
HEALTH CARE 0.1%
Life Sciences Tools & Services 0.1%
Sartorius (EUR) 58 17
Total Health Care 17
Total Preferred Stocks (Cost $14) 17
SHORT-TERM INVESTMENTS 0.2%
Money Market Funds 0.2%
State Street Institutional U.S. Government Money Market Fund, 3.74% (4) 32,230 32
Total Short-Term Investments (Cost $32) 32
SECURITIES LENDING COLLATERAL 0.7%
Investments in a Pooled Account through Securities Lending Program with State Street Bank and Trust Company 0.7%
Money Market Funds 0.7%
T. Rowe Price Treasury Reserve Fund, 3.75% (4)(5) 110,565 111
Total Investments in a Pooled Account through Securities Lending Program with State Street Bank and Trust Company 111
Total Securities Lending Collateral (Cost $111) 111
Total Investments in Securities
100.7% of Net Assets (Cost $15,224)
$16,433
Shares are denominated in U.S. dollars unless otherwise noted.
(1) See Note 2. Level 3 in fair value hierarchy.
(2) Non-income producing.
(3) See Note 3. All or a portion of this security is on loan at December 31, 2025.
(4) Seven-day yield
6
T. ROWE PRICE HEALTH CARE ETF
(5) Affiliated Companies
ADR American Depositary Receipts
CHF Swiss Franc
EUR Euro
7
T. ROWE PRICE HEALTH CARE ETF
AFFILIATED COMPANIES
($000s)
The fund may invest in certain securities that are considered affiliated companies. As defined by the 1940 Act, an affiliated company is one in which the fund owns 5% or more of the outstanding voting securities, or a company that is under common ownership or control. The following securities were considered affiliated companies for all or some portion of the period ended December 31, 2025. Net realized gain (loss), investment income, change in net unrealized gain/loss, and purchase and sales cost reflect all activity for the period then ended.
Affiliate Net Realized Gain
(Loss)
Changes in Net
Unrealized
Gain/Loss
Investment
Income
T. Rowe Price Treasury Reserve Fund $- $- $-++
Totals $-# $- $-+
Supplementary Investment Schedule
Affiliate Value
12/31/24
Purchase
Cost
Sales
Cost
Value
12/31/25
T. Rowe Price Treasury Reserve Fund $- ¤ ¤ $111
Total $111^
++ Excludes earnings on securities lending collateral, which are subject to rebates and fees as described in Note 3.
# Capital gain distributions from underlying Price funds represented $0 of the net realized gain (loss).
+ Investment income comprised $0 of dividend income and $0 of interest income.
¤ Purchase and sale information not shown for cash management funds.
^ The cost basis of investments in affiliated companies was $111.
The accompanying notes are an integral part of these financial statements.
8
T. ROWE PRICE HEALTH CARE ETF
December 31, 2025
STATEMENT OF ASSETS AND LIABILITIES
($000s, except shares and per share amounts)
Assets
Investments in securities, at value (cost $15,224) $16,433 
Dividends receivable 7 
Total assets 16,440 
Liabilities
Obligation to return securities lending collateral 111 
Investment management and administrative fees payable 6 
Total liabilities 117 
NET ASSETS $16,323
Net Assets Consists of:
Total distributable earnings (loss) $1,092 
Paid-in capital applicable to 550,000 shares of $0.0001 par value
capital stock outstanding; 4,000,000,000 shares of the Corporation authorized
15,231 
NET ASSETS $16,323
NET ASSET VALUE PER SHARE $29.68
The accompanying notes are an integral part of these financial statements.
9
T. ROWE PRICE HEALTH CARE ETF
STATEMENT OF OPERATIONS
($000s)
6/11/25
Through
12/31/25
Investment Income (Loss)
Dividend income $78 
Investment management and administrative expense 32 
Net investment income 46 
Realized and Unrealized Gain / Loss
Net realized gain (loss)
Securities (72)
In-kind redemptions 1,428 
Net realized gain 1,356 
Change in net unrealized gain / loss on securities 1,209 
Net realized and unrealized gain / loss 2,565 
INCREASE IN NET ASSETS FROM OPERATIONS $2,611
The accompanying notes are an integral part of these financial statements.
10
T. ROWE PRICE HEALTH CARE ETF
STATEMENT OF CHANGES IN NET ASSETS
($000s)
6/11/25
Through
12/31/25
Increase (Decrease) in Net Assets
Operations
Net investment income $46 
Net realized gain 1,356 
Change in net unrealized gain / loss 1,209 
Increase in net assets from operations 2,611 
Distributions to shareholders
Net earnings (89)
Capital share transactions*
Shares sold 21,068 
Shares redeemed (7,267)
Increase in net assets from capital share transactions 13,801 
Net Assets
Increase during period 16,323 
Beginning of period - 
End of period $16,323
*Share information (000s)
Shares sold 800 
Shares redeemed (250)
Increase in shares outstanding 550 
The accompanying notes are an integral part of these financial statements.
11
T. ROWE PRICE HEALTH CARE ETF
NOTES TO FINANCIAL STATEMENTS
T. Rowe Price Exchange-Traded Funds, Inc. (the corporation) is registered under the Investment Company Act of 1940 (the 1940 Act). The Health Care ETF (the fund) is a nondiversified, open-end management investment company established by the corporation. The fund incepted on June 11, 2025. The fund seeks long-term capital appreciation.
NOTE 1 - SIGNIFICANT ACCOUNTING POLICIES
Basis of Preparation
The fund is an investment company and follows accounting and reporting guidance in the Financial Accounting Standards Board (FASB) Accounting Standards CodificationTopic 946 (ASC 946). The accompanying financial statements were prepared in accordance with accounting principles generally accepted in the United States of America (GAAP), including, but not limited to, ASC 946. GAAP requires the use of estimates made by management. Management believes that estimates and valuations are appropriate; however, actual results may differ from those estimates, and the valuations reflected in the accompanying financial statements may differ from the value ultimately realized upon sale or maturity.
Investment Transactions, Investment Income, and Distributions
Investment transactions are accounted for on the trade date basis. Income and expenses are recorded on the accrual basis. Realized gains and losses are reported on the identified cost basis. Income tax-related interest and penalties, if incurred, are recorded as income tax expense. Dividends received from other investment companies are reflected as dividend income; capital gain distributions are reflected as realized gain/loss. Dividend income and capital gain distributions are recorded on the ex-dividend date. Non-cash dividends, if any, are recorded at the fair market value of the asset received. Proceeds from litigation payments, if any, are included in either net realized gain (loss) or change in net unrealized gain/loss from securities. Distributions to shareholders are recorded on the ex-dividend date. Income distributions, if any, are declared and paid annually. A capital gain distribution, if any, may also be declared and paid by the fund annually. Dividends and distributions cannot be automatically reinvested in additional shares of the fund.
12
T. ROWE PRICE HEALTH CARE ETF
Currency Translation
Assets, including investments, and liabilities denominated in foreign currencies are translated into U.S. dollar values each day at the prevailing exchange rate, using the mean of the bid and asked prices of such currencies against U.S. dollars as provided by an outside pricing service. Purchases and sales of securities, income, and expenses are translated into U.S. dollars at the prevailing exchange rate on the respective date of such transaction. The effect of changes in foreign currency exchange rates on realized and unrealized security gains and losses is not bifurcated from the portion attributable to changes in market prices.
Capital Transactions
The fund issues and redeems shares at its net asset value (NAV) only with Authorized Participants and only in large blocks of 50,000 shares (each, a "Creation Unit"). The fund's NAV per share is computed at the close of the New York Stock Exchange (NYSE), normally 4 p.m. Eastern time, each day the NYSE is open for business. However, the NAV per share may be calculated at a time other than the normal close of the NYSE if trading on the NYSE is restricted, if the NYSE closes earlier, or as may be permitted by the SEC. Individual fund shares may not be purchased or redeemed directly with the fund. An Authorized Participant may purchase or redeem a Creation Unit of the fund each business day that the fund is open in exchange for the delivery of a designated portfolio of in-kind securities and/or cash. When purchasing or redeeming Creation Units, Authorized Participants are also required to pay a fixed and/or variable purchase or redemption transaction fee as well as any applicable additional variable charge to defray the transaction cost to a fund.
Individual fund shares may be purchased and sold only on a national securities exchange through brokers. Shares are listed for trading on Nasdaq Stock Market LLC and because the shares will trade at market prices rather than NAV, shares may trade at prices greater than NAV (at a premium), at NAV, or less than NAV (at a discount).
Indemnification
In the normal course of business, the fund may provide indemnification in connection with its officers and directors, service providers, and/or private company investments. The fund's maximum exposure under these arrangements is unknown; however, the risk of material loss is currently considered to be remote.
13
T. ROWE PRICE HEALTH CARE ETF
NOTE 2 - VALUATION
Fair Value
The fund's financial instruments are valued at the close of the NYSE and are reported at fair value, which GAAP defines as the price that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants at the measurement date. The fund's Board of Directors (the Board) has designated T. Rowe Price Associates, Inc. as the fund's valuation designee (Valuation Designee). Subject to oversight by the Board, the Valuation Designee performs the following functions in performing fair value determinations: assesses and manages valuation risks; establishes and applies fair value methodologies; tests fair value methodologies; and evaluates pricing vendors and pricing agents. The duties and responsibilities of the Valuation Designee are performed by its Valuation Committee. The Valuation Designee provides periodic reporting to the Board on valuation matters.
Various valuation techniques and inputs are used to determine the fair value of financial instruments. GAAP establishes the following fair value hierarchy that categorizes the inputs used to measure fair value:
Level 1 - quoted prices (unadjusted) in active markets for identical financial instruments that the fund can access at the reporting date
Level 2 - inputs other than Level 1 quoted prices that are observable, either directly or indirectly (including, but not limited to, quoted prices for similar financial instruments in active markets, quoted prices for identical or similar financial instruments in inactive markets, interest rates and yield curves, implied volatilities, and credit spreads)
Level 3 - unobservable inputs (including the Valuation Designee's assumptions in determining fair value)
Observable inputs are developed using market data, such as publicly available information about actual events or transactions, and reflect the assumptions that market participants would use to price the financial instrument. Unobservable inputs are those for which market data are not available and are developed using the best information available about the assumptions that market participants would use to price the financial instrument. GAAP requires valuation techniques to maximize the use of relevant observable inputs and minimize the use of unobservable inputs. When multiple inputs are used to derive fair value, the financial instrument is assigned to the level within the fair value hierarchy based on the lowest-level input that is significant to the fair value of the financial
14
T. ROWE PRICE HEALTH CARE ETF
instrument. Input levels are not necessarily an indication of the risk or liquidity associated with financial instruments at that level but rather the degree of judgment used in determining those values.
Valuation Techniques
Equity securities, including exchange-traded funds, listed or regularly traded on a securities exchange or in the over-the-counter (OTC) market are valued at the last quoted sale price or, for certain markets, the official closing price at the time the valuations are made. A security that is listed or traded on more than one exchange is valued at the quotation on the exchange determined to be the primary market for such security. Listed securities not traded on a particular day are valued at the mean of the closing bid and asked prices for domestic securities and the last quoted sale or closing price for international securities.
The last quoted prices of non-U.S. equity securities may be adjusted to reflect the fair value of such securities at the close of the NYSE, if the Valuation Designee determines that developments between the close of a foreign market and the close of the NYSE will affect the value of some or all of the fund's portfolio securities. Each business day, the Valuation Designee uses information from outside pricing services to evaluate the quoted prices of portfolio securities and, if appropriate, decides whether it is necessary to adjust quoted prices to reflect fair value by reviewing a variety of factors, including developments in foreign markets, the performance of U.S. securities markets, and the performance of instruments trading in U.S. markets that represent foreign securities and baskets of foreign securities. The Valuation Designee uses outside pricing services to provide it with quoted prices and information to evaluate or adjust those prices. The Valuation Designee cannot predict how often it will use quoted prices or how often it will determine it necessary to adjust those prices to reflect fair value.
Investments in mutual funds are valued at the mutual fund's closing NAV per share on the day of valuation. Assets and liabilities other than financial instruments, including short-term receivables and payables, are carried at cost, or estimated realizable value, if less, which approximates fair value.
Investments for which market quotations are not readily available or deemed unreliable are valued at fair value as determined in good faith by the Valuation Designee. The Valuation Designee has adopted methodologies for determining the fair value of investments for which market quotations are not readily available or deemed unreliable, including the use of other pricing sources. Factors used in determining fair value vary by type of investment and may include market or investment specific considerations. The Valuation Designee typically will afford the greatest weight to actual prices in arm's length transactions, to the extent they
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T. ROWE PRICE HEALTH CARE ETF
represent orderly transactions between market participants, transaction information can be reliably obtained, and prices are deemed representative of fair value. However, the Valuation Designee may also consider other valuation methods such as market-based valuation multiples; a discount or premium from market value of a similar, freely traded security of the same issuer; discounted cash flows; yield to maturity; or some combination. Fair value determinations are reviewed on a regular basis. Because any fair value determination involves a significant amount of judgment, there is a degree of subjectivity inherent in such pricing decisions. Fair value prices determined by the Valuation Designee could differ from those of other market participants, and it is possible that the fair value determined for a security may be materially different from the value that could be realized upon the sale of that security.
Valuation Inputs
The following table summarizes the fund's financial instruments, based on the inputs used to determine their fair values on December 31, 2025 (for further detail by category, please refer to the accompanying Portfolio of Investments):
($000s) Level 1 Level 2 Level 3 Total Value
Assets
Common Stocks $16,207 $60 $6 $16,273
Preferred Stocks - 17 - 17
Short-Term Investments 32 - - 32
Securities Lending Collateral 111 - - 111
Total $16,350 $77 $6 $16,433
NOTE 3 - OTHER INVESTMENT TRANSACTIONS
Consistent with its investment objective, the fund engages in the following practices to manage exposure to certain risks and/or to enhance performance. The investment objective, policies, program, and risk factors of the fund are described more fully in the fund's prospectus and Statement of Additional Information.
Securities Lending
The fund may lend its securities to approved borrowers to earn additional income. Its securities lending activities are administered by a lending agent in accordance with a securities lending agreement. Security loans generally do not have stated
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T. ROWE PRICE HEALTH CARE ETF
maturity dates, and the fund may recall a security at any time. The fund receives collateral in the form of cash or U.S. government securities. Collateral is maintained over the life of the loan in an amount not less than the value of loaned securities; any additional collateral required due to changes in security values is delivered to the fund the next business day. Cash collateral is invested in accordance with investment guidelines approved by fund management. Additionally, the lending agent indemnifies the fund against losses resulting from borrower default. Although risk is mitigated by the collateral and indemnification, the fund could experience a delay in recovering its securities and a possible loss of income or value if the borrower fails to return the securities, collateral investments decline in value, and the lending agent fails to perform. Any non-cash collateral received cannot be sold, re-invested or pledged by the fund, except in the event of borrower default. Securities lending revenue consists of earnings on invested collateral and borrowing fees, net of any rebates to the borrower, compensation to the lending agent, and other administrative costs. In accordance with GAAP, investments made with cash collateral are reflected in the accompanying financial statements, but collateral received in the form of securities is not. At December 31, 2025, the value of loaned securities was $109,000; the value of cash collateral and related investments was $111,000.
Other
Purchases and sales of portfolio securities excluding in-kind transactions and short-term securities aggregated $15,538,000 and $5,764,000, respectively, for the period ended December 31, 2025. Portfolio securities received and delivered through in-kind transactions aggregated $10,778,000 and $6,703,000, respectively, for the period ended December 31, 2025.
NOTE 4 - FEDERAL INCOME TAXES
Generally, no provision for federal income taxes is required since the fund intends to qualify as a regulated investment company under Subchapter M of the Internal Revenue Code and distribute to shareholders all of its taxable income and gains. Distributions determined in accordance with federal income tax regulations may differ in amount or character from net investment income and realized gains for financial reporting purposes.
The fund files U.S. federal, state, and local tax returns as required. The fund's tax returns are subject to examination by the relevant tax authorities until expiration of the applicable statute of limitations, which is generally three years after the filing of the tax return but which can be extended to six years in certain circumstances.
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Capital accounts within the financial reporting records are adjusted for permanent book/tax differences to reflect tax character but are not adjusted for temporary differences. The permanent book/tax adjustments, if any, have no impact on results of operations or net assets. The permanent book/tax adjustments relate primarily to redemptions in kind and the character of income on passive foreign investment companies.
The tax character of distributions paid for the period presented is as follows:
($000s)
December 31,
2025
Ordinary income (including short-term capital gains, if any) $89
At December 31, 2025, the tax-basis cost of investments, (including derivatives, if any) and gross unrealized appreciation and depreciation were as follows:
($000s)
Cost of investments $15,252
Unrealized appreciation $1,382
Unrealized depreciation (201)
Net unrealized appreciation (depreciation) $1,181
At December 31, 2025, the tax-basis components of accumulated net earnings (loss) were as follows:
($000s)
Net unrealized appreciation (depreciation) $1,181
Loss carryforwards and deferrals (89)
Total distributable earnings (loss) $1,092
Temporary differences between book-basis and tax-basis components of total distributable earnings (loss) arise when certain items of income, gain, or loss are recognized in different periods for financial statement purposes versus for tax purposes; these differences will reverse in a subsequent reporting period. The temporary differences relate primarily to the deferral of losses from wash sales and the realization of gains/losses on passive foreign investment companies. The loss carryforwards and deferrals primarily relate to capital loss carryforwards and
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T. ROWE PRICE HEALTH CARE ETF
late-year ordinary loss deferrals. Capital loss carryforwards are available indefinitely to offset future realized capital gains. The fund has elected to defer certain losses to the first day of the following fiscal year for late-year ordinary loss deferrals.
NOTE 5 - RELATED PARTY TRANSACTIONS
The fund is managed by T. Rowe Price Associates, Inc. (Price Associates), a wholly owned subsidiary of T. Rowe Price Group, Inc. (Price Group). Price Associates has entered into a sub-advisory agreement(s) with one or more of its wholly owned subsidiaries, to provide investment advisory services to the fund. The investment management and administrative agreement between the fund and Price Associates provides for an annual all-inclusive fee equal to 0.44% of the fund's average daily net assets. The fee is computed daily and paid monthly. The all-inclusive fee covers investment management services and ordinary, recurring operating expenses but does not cover interest and borrowing expenses; taxes; brokerage commissions and other transaction costs; fund proxy expenses; and nonrecurring and extraordinary expenses. All costs related to organization and offering of the fund are borne by Price Associates.
T. Rowe Price Investment Services, Inc. (Investment Services) serves as distributor to the fund. Pursuant to an underwriting agreement, no compensation for any distribution services provided is paid to Investment Services by the fund.
Effective November 12, 2025, cash collateral from securities lending, if any, is invested in the T. Rowe Price Treasury Reserve Fund (the Price Reserve Fund), a money market fund offered as a short-term investment option to mutual funds, trusts, and other accounts managed by Price Associates or its affiliates and is not available for direct purchase by members of the public. Prior to November 12, 2025, cash collateral from securities lending, if any, was invested in the T. Rowe Price Government Reserve Fund. The Price Reserve Fund does not pay investment management fees.
As of December 31, 2025, T. Rowe Price Group, Inc., or its wholly owned subsidiaries, owned 350,000 shares of the fund, representing 64% of the fund's net assets.
The fund may participate in securities purchase and sale transactions with other funds or accounts advised by Price Associates (cross trades), in accordance with procedures adopted by the fund's Board and Securities and Exchange Commission rules, which require, among other things, that such purchase and
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sale cross trades be effected at the independent current market price of the security. During the period ended December 31, 2025, the fund had no purchases or sales cross trades with other funds or accounts advised by Price Associates.
NOTE 6 - SEGMENT REPORTING
Operating segments are defined as components of a company that engage in business activities and for which discrete financial information is available and regularly reviewed by the chief operating decision maker (CODM) in deciding how to allocate resources and assess performance. The Management Committee of Price Associates acts as the fund's CODM. The fund makes investments in accordance with its investment objective as outlined in the Prospectus and is considered one reportable segment because the CODM allocates resources and assesses the operating results of the fund on the whole.
The fund's revenue is derived from investments in a portfolio of securities. The CODM allocates resources and assesses performance based on the operating results of the fund, which is consistent with the results presented in the statement of operations, statement of changes in net assets and financial highlights. The CODM compares the fund's performance to its benchmark index and evaluates the positioning of the fund in relation to its investment objective. The measure of segment assets is net assets of the fund which is disclosed in the statement of assets and liabilities.
The accounting policies of the segment are the same as those described in the summary of significant accounting policies. The financial statements include all details of the segment assets, segment revenue and expenses; and reflect the financial results of the segment.
NOTE 7 - OTHER MATTERS
Unpredictable environmental, political, social and economic events, including but not limited to, environmental or natural disasters, war and conflict, terrorism, geopolitical and regulatory developments (including trading and tariff arrangements), and public health epidemics or threats, may significantly affect the economy and the markets and issuers in which a fund invests. The extent and duration of such events and resulting market disruptions cannot be predicted. These and other similar events may cause instability across global markets, including reduced liquidity and disruptions in trading markets, while some events
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may affect certain geographic regions, countries, sectors, and industries more significantly than others, and exacerbate other pre-existing political, social, and economic risks. The fund's performance could be negatively impacted if the value of a portfolio holding were harmed by these or such events.
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T. ROWE PRICE HEALTH CARE ETF
REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
To the Board of Directors of T. Rowe Price Exchange-Traded Funds, Inc. and Shareholders of T. Rowe Price Health Care ETF
Opinion on the Financial Statements
We have audited the accompanying statement of assets and liabilities, including the portfolio of investments, of T. Rowe Price Health Care ETF (one of the funds constituting T. Rowe Price Exchange-Traded Funds, Inc., referred to hereafter as the "Fund") as of December 31, 2025, and the related statements of operations and changes in net assets, including the related notes, and the financial highlights for the period June 11, 2025 (inception) through December 31, 2025 (collectively referred to as the "financial statements"). In our opinion, the financial statements present fairly, in all material respects, the financial position of the Fund as of December 31, 2025, and the results of its operations, changes in its net assets, and the financial highlights for the period June 11, 2025 (inception) through December 31, 2025 in conformity with accounting principles generally accepted in the United States of America.
Basis for Opinion
These financial statements are the responsibility of the Fund's management. Our responsibility is to express an opinion on the Fund's financial statements based on our audit. We are a public accounting firm registered with the Public Company Accounting Oversight Board (United States) (PCAOB) and are required to be independent with respect to the Fund in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.
We conducted our audit of these financial statements in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement, whether due to error or fraud.
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T. ROWE PRICE HEALTH CARE ETF
REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
(CONTINUED)
Our audit included performing procedures to assess the risks of material misstatement of the financial statements, whether due to error or fraud, and performing procedures that respond to those risks. Such procedures included examining, on a test basis, evidence regarding the amounts and disclosures in the financial statements. Our audit also included evaluating the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of the financial statements. Our procedures included confirmation of securities owned as of December 31, 2025 by correspondence with the custodian. We believe that our audit provides a reasonable basis for our opinion.
/s/ PricewaterhouseCoopers LLP
Baltimore, Maryland
February 18, 2026
We have served as the auditor of one or more investment companies in the T. Rowe Price group of investment companies since 1973.
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T. ROWE PRICE HEALTH CARE ETF
TAX INFORMATION (UNAUDITED) FOR THE TAX YEAR ENDED 12/31/25
We are providing this information as required by the Internal Revenue Code. The amounts shown may differ from those elsewhere in this report because of differences between tax and financial reporting requirements.
The fund's distributions to shareholders included:
For taxable non-corporate shareholders, $69,000 of the fund's income represents qualified dividend income subject to a long-term capital gains tax rate of not greater than 20%.
For corporate shareholders, $69,000 of the fund's income qualifies for the dividends-received deduction.
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1307 Point Street
Baltimore, Maryland 21231
Call 1-800-638-5660 to request a prospectus or summary prospectus; each includes investment objectives, risks, fees, expenses, and other information that you should read and consider carefully before investing.
T. Rowe Price Investment Services, Inc.
ETF1194-050 02/26

Item 8. Changes in and Disagreements with Accountants for Open-EndManagement Investment Companies.

Not applicable.

Item 9. Proxy Disclosures for Open-EndManagement Investment Companies.

Not applicable.

Item 10. Remuneration Paid to Directors, Officers, and Others of Open-EndManagement Investment Companies.

Remuneration paid to Directors is included in Item 7 of this Form N-CSR.

Item 11. Statement Regarding Basis for Approval of Investment Advisory Contract.

If applicable, see Item 7.

Item 12. Disclosure of Proxy Voting Policies and Procedures for Closed-EndManagement Investment Companies.

Not applicable.

Item 13. Portfolio Managers of Closed-EndManagement Investment Companies.

Not applicable.

Item 14. Purchases of Equity Securities by Closed-EndManagement Investment Company and Affiliated Purchasers.

Not applicable.

Item 15. Submission of Matters to a Vote of Security Holders.

There has been no change to the procedures by which shareholders may recommend nominees to the registrant's board of directors.

Item 16. Controls and Procedures.

(a) The registrant's principal executive officer and principal financial officer have evaluated the registrant's disclosure controls and procedures within 90 days of this filing and have concluded that the registrant's disclosure controls and procedures were effective, as of that date, in ensuring that information required to be disclosed by the registrant in this Form N-CSRwas recorded, processed, summarized, and reported timely.

(b) The registrant's principal executive officer and principal financial officer are aware of no change in the registrant's internal control over financial reporting that occurred during the period covered by this report that has materially affected, or is reasonably likely to materially affect, the registrant's internal control over financial reporting.

Item 17. Disclosure of Securities Lending Activities for Closed-EndManagement Investment Companies.

Not applicable.

Item 18. Recovery of Erroneously Awarded Compensation.

Not applicable.

Item 19. Exhibits.

(a)(1)  

N-CSR

    (2)  

Listing standards relating to recovery of erroneously awarded compensation: not applicable.

    (3)  

30a-2(a)

(b)     

30a-2(b)

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

T. Rowe Price Exchange-Traded Funds, Inc.
By

/s/ David Oestreicher

   
David Oestreicher
Principal Executive Officer
Date  February 18, 2026

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.

By

/s/ David Oestreicher

   
David Oestreicher
Principal Executive Officer
Date 

February 18, 2026

By

/s/ Alan S. Dupski

   
Alan S. Dupski
Principal Financial Officer
Date 

February 18, 2026

T. Rowe Price Exchange-Traded Funds Inc. published this content on February 23, 2026, and is solely responsible for the information contained herein. Distributed via EDGAR on February 23, 2026 at 16:31 UTC. If you believe the information included in the content is inaccurate or outdated and requires editing or removal, please contact us at [email protected]