NIST - National Institute of Standards and Technology
09/15/2026 | Press release | Archived content
Advances in the Measurement of Vitamin D Binding Protein
Published
September 15, 2026
Author(s)
Karen Phinney, Lisa Kilpatrick
Abstract
Vitamin D binding protein (DBP) is a polymorphic protein known for its function in transporting vitamin D metabolites. DBP also plays several other important roles in the body's response to tissue damage and inflammation. Measurement of DBP is fundamental to understanding its relationship to vitamin D status and to elucidating potential links between DBP concentration and various health outcomes. Early studies on DBP primarily used antibody-based techniques for quantification, and mass spectrometry-based methods have been reported during the past decade. This review will outline the different methodologies used in DBP studies, describe their advantages and limitations, and highlight some future trends.
Citation
Analytical and Bioanalytical Chemistry
Pub Type
Journals
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Keywords
immunoassay, mass spectrometry, metabolite, protein quantification, vitamin D
Citation
Phinney, K. and Kilpatrick, L. (2026), Advances in the Measurement of Vitamin D Binding Protein, Analytical and Bioanalytical Chemistry, [online], https://doi.org/10.1007/s00216-026-06815-5, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=962203 (Accessed September 19, 2026)
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NIST - National Institute of Standards and Technology published this content on September 15, 2026, and is solely responsible for the information contained herein. Distributed via Public Technologies (PUBT), unedited and unaltered, on September 19, 2026 at 09:13 UTC. If you believe the information included in the content is inaccurate or outdated and requires editing or removal, please contact us at [email protected]