Material Event (Form 8-K)

Item 8.01. Other Events.

On September 18, 2025, Palisade Bio, Inc. (the "Company") convened and then determined to adjourn, without conducting any business, a special meeting of stockholders (the "Special Meeting") because the Company did not have a sufficient number of shares of the Company's Common Stock present in person or represented by proxy at the Special Meeting to constitute a quorum. The adjourned Special Meeting will reconvene on Friday, September 26, 2025 at 10:00 a.m. Pacific Time.

The close of business on July 28, 2025 will continue to be the record date for the determination of stockholders of the Company entitled to vote at the Special Meeting. No changes have been made to the proposals to be voted on by stockholders at the Special Meeting. Stockholders who have previously submitted their proxy or otherwise voted and do not want to change their vote do not need to take any action. Stockholders may cast their votes by following the instructions set forth in the Company's definitive proxy statement on Schedule 14A which was filed with the Securities and Exchange Commission on August 18, 2025 which is available on the SEC's website at www.sec.gov, and the voting platform at www.proxydocs.com/PALI.