ADM Introduces PRIOME® Joint Health Postbiotic for Pets

CHICAGO - ADM (NYSE: ADM), a global leader in innovative solutions from nature, is expanding its PRIOME®* postbiotics portfolio for pets with the addition of PRIOME® Joint Health (heat-treated Lacticaseibacillus rhamnosus NCIMB 30446). Preliminary in vitro and model organism research show PRIOME®JH has potential to support joint health, cartilage function, collagen production, muscle maintenance, gut barrier function and healthy weight management.¹

A growing body of research indicates the interplay between the gut microbiome and joint health, also called the gut-joint axis. An imbalance of the gut microbiome can lead to increased intestinal permeability, allowing bacteria and related compounds to cross the intestinal barrier and enter systemic circulation. Research suggests that this transfer of microbial metabolites often initiates a variety of physiological responses, serving as a possible mechanistic link between the gut microbiome and joint health.² Crucially, evidence of this connection has been demonstrated in dogs: a study comparing healthy dogs with those diagnosed with hip or elbow arthritis found measurable differences in gut microbial community composition and reduced bacterial diversity in arthritic animals, supporting the existence of a microbiome-joint axis in canine patients.³ These findings point to a compelling opportunity to support the gut microbiome with probiotic, prebiotic and postbiotic ingredients and address joint health from the inside out. Recently, these findings were published in the renowned journal, Cells.

"Joint health is among pet parents' top concerns for their pet's quality of life, as it can affect not only mobility but also energy, healthy aging and activity levels,⁴ " said Mark Lotsch, Global President, Health & Wellness at ADM. "Our postbiotic ingredient is an innovative science-backed solution that can support wellness in a variety of pet-friendly applications, providing pet parents with several convenient and easy-to-use options in pet care."

As inanimate microorganisms, postbiotic efficacy is not reliant on maintenance of cell viability, and functionality is maintained throughout manufacturing and stability testing. Functionality of ADM's PRIOME® postbiotics are thoroughly validated by application scientists across a wide range of finished product formats, including powders, soft chews, baked treats, extruded treats and chews, liquids, dry kibble and wet food.^‡ Product manufacturers can easily incorporate PRIOME®postbiotics into various formula matrices at appropriate inclusion rates that do not impact the taste or smell of finished products, supporting pet palatability.

"We combine deep formulation expertise with a robust portfolio of microbiome solutions - including prebiotics, probiotics and postbiotics - to help brands bring consumer-driven pet products to market," said James Kyffin, Global Director, Pet and Animal Wellbeing at ADM. "From custom formulations to market-ready solutions, we enable convenient, on-trend innovations backed by clinically studied ingredients that deliver real value for today's pet parents."

Lacticaseibacillus rhamnosus NCIMB 30446† is an Association of American Feed Control Officials (AAFCO)-accepted biotic species and ADM is a National Animal Supplement Council (NASC)-preferred supplier. Other offerings in ADM's PRIOME®postbiotic suite include Oral Care, Metabolic Health, Gut Health, Mental Wellbeing and Skin Health. Learn more about ADM's science-backed microbiome solutions for pets here.

*PRIOME®is a trademark registered in the name of ADM International Sàrl.
† Listed as Lactobacillus casei in the AAFCO Official Publication
‡Regulatory compliance for ingredient use, permitted product types, and product claims remain the responsibility of the brand owner or guarantor
¹Based on ADM's pre-clinical research
²Hernandez C.J., 2018. Curr. Rheumatol. Rep. 19(12):77
³Cintio M. et al. Vet Sci. 2020 Jul 14;7(3):92
⁴Schmutz et al., 2022. Sci. Reports. 12:12225

About ADMADM unlocks the power of nature to enrich the quality of life. We're an essential global agricultural supply chain manager and processor, providing food security by connecting local needs with global capabilities. We're a premier human and animal nutrition provider, offering one of the industry's broadest portfolios of ingredients and solutions from nature. We're a trailblazer in health and well-being, with an industry-leading range of products for consumers looking for new ways to live healthier lives. We're a cutting-edge innovator, guiding the way to a future of new bio-based consumer and industrial solutions. And we're leading in business-driven sustainability efforts that support a strong agricultural sector, resilient supply chains, and a vast and growing bioeconomy. Around the globe, our expertise and innovation are meeting critical needs from harvest to home. Learn more at https://www.adm.com.

ADM Media Relations
Jackie Anderson
[email protected]
312-634-8484