Management Change/Compensation, Proxy Results (Form 8-K)

Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

(e) As reported below in Item 5.07 of this Current Report on Form 8-K (the "Report"), Synlogic, Inc. (the "Company") held its 2025 annual meeting of stockholders (the "Annual Meeting") on December 15, 2025, at which the Company's stockholders approved the adoption of the Synlogic, Inc. 2025 Equity Incentive Plan (the "2025 Plan"). The 2025 Plan authorizes for issuance an aggregate of 1,000,000 shares of common stock, par value $0.001 per share, of the Company (the "Common Stock"), plus 332,468 additional shares of Common Stock, which may be issued under the 2025 Plan if awards outstanding under the 2015 Equity Incentive Award Plan (the "2015 Plan") are cancelled or expire on or after December 15, 2025.

The 2025 Plan is the successor to the 2015 Plan, and accordingly, no further awards will be made under the 2015 Plan and any awards granted under the 2015 Plan prior to the date of the Annual Meeting will remain outstanding under the 2015 Plan and will continue to vest and/or become exercisable in accordance with their original terms and conditions.

A summary of the material terms of the 2025 Plan is set forth in the Company's definitive proxy statement on Schedule 14A filed with the Securities and Exchange Commission on November 12, 2025 (the "Proxy Statement"), under the heading "Approval of the Synlogic, Inc. 2025 Equity Incentive Plan," and is incorporated herein by reference. Such description is qualified in its entirety by reference to the actual terms of the 2025 Plan a copy of which is attached as Exhibit 10.1 to this Report and is incorporated herein by reference.

Item 5.07 Submission of Matters to a Vote of Security Holders.

(a) On December 15, 2025, the Company held its Annual Meeting. At the Annual Meeting, a quorum of 10,292,327 shares of the Company's common stock, or 87.97% of the outstanding shares of common stock entitled to vote as of the record date of October 24, 2025, were present or represented by proxy.

(b) The following actions were taken at the Annual Meeting:

1. The following nominees were reelected to serve on the Company's board of directors (the "Board of Directors") as Class I directors until the Company's 2028 annual meeting of stockholders, based on the following votes:

After the Annual Meeting, Edward Mathers continued to serve as a Class II Director for a term that expires at the 2026 annual meeting, and Peter Barrett, Ph.D. continued to serve as a Class III Director for a term that expires at the 2027 annual meeting.

2. The Company's stockholders approved, in a non-binding advisory vote, the compensation of the Company's named executive officers, as disclosed in the Proxy Statement, based on the following votes:

3. The Company's stockholders approved the adoption of the 2025 Plan, based on the following votes:

4. The selection of KPMG LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2025 was ratified, based on the following votes: