APhA alarmed by claims of harm from acetaminophen without substantive science

As the medication experts, APhA affirms there has been no new evidence in two decades that the use of acetaminophen (Tylenol) in pregnancy causes autism. The two most reputable studies, including one last year, found no significant associations between the use of acetaminophen during pregnancy and children's risk of autism, ADHD, or intellectual disability. The American public relies upon our nation's pharmacists to make recommendations for the use of products to treat minor, self-limiting illnesses with nonprescription drugs, including acetaminophen. As the health care providers responsible for ensuring the appropriate outcomes from medicines, including nonprescription drugs, pharmacists rigorously review the science to ensure their recommendations are best for the patients under their care. Americans should continue to trust the advice of their personal pharmacist and other health care providers.

As stated by FDA, at usual doses for treating fever in pregnancy, acetaminophen remains safe and effective. The occurrence of untreated fever in pregnancy has serious adverse implications for the fetus. Acetaminophen is the only FDA-approved medication known to be safe at usual doses in people who are pregnant. This has not changed.

While it is appropriate to continuously monitor drug safety signals and review emerging research, claims that are not rooted in science are confusing to patients and health care providers who are caring for and counseling patients during pregnancy.

APhA urges patients to talk with their trusted pharmacists. Based on the current literature, acetaminophen remains a safe option for people who are pregnant when used appropriately. APhA will continue to defend science and uphold rigorous evidence-based evaluations for our patients, free from any influence from special interests.