Material Event (Form 8-K)

Item 8.01 Other Events.

On July 9, 2026, iSpecimen Inc. (the "Company") completed Milestone 3 in the Company's digital transformation program powered by SalesStack Solutions. Pursuant to Section 3.1 of the Definitive Software Purchase and Services Agreement between the Company and Sales Stack Solutions Corp. (the "SalesStack Agreement"), filed as Exhibit 10.46 to the Company's Registration Statement on Form S-1/A filed on June 11, 2025, the Company made a payment of $700,000 upon completion of Milestone 3. This milestone delivers additional marketplace features, broader geographic rollout, and deeper integrations with partner ecosystems, building upon the system integration and marketplace activation achieved in Milestone 2. The Company previously disclosed the completion of Milestone 1 and Milestone 2 under the SalesStack Agreement on Current Reports on Form 8-K filed on August 21, 2025 and February 6, 2026, respectively.