Statement of Changes in Beneficial Ownership (Form 4)

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b). Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person * Warbington Timothy 2. Issuer Name and Ticker or Trading Symbol CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. [CELZ] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director __X__ 10% Owner __X__ Officer (give title below) _____ Other (specify below) President & CEO (Last) (First) (Middle) 211 E. OSBORN ROAD 3. Date of Earliest Transaction (Month/Day/Year) 09/24-05:00/2026 (Street) PHOENIX, AZ 85012 4. If Amendment, Date Original Filed (Month/Day/Year) 6. Individual or Joint/Group Filing (Check Applicable Line) ___ Form filed by One Reporting Person _X_ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 09/24-05:00/2026 A 1,000,000 A (1) 1,034,904(2) I(2) By entity(2)

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Warbington Timothy 211 E. OSBORN ROAD PHOENIX, AZ 85012	X	X	President & CEO
Creative Acquisition Corp. 2375 E. CAMELBACK RD SUITE 600 PHOENIX, AZ 85016	X

Signatures

/s/ Timothy Warbington		09/25/2026
**Signature of Reporting Person		Date
/s/ Timothy Warbington, Chairman and CEO of Creative Acquisition Corp.		09/25/2026
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	The shares of common stock were issued to Creative Acquisition Corp. ("CAC") pursuant to a Stock Purchase Agreement dated September 24, 2026 (the "SPA"), between CAC and the Issuer, pursuant to which the Issuer purchased 4,000,000 shares of common stock of BioDefense, Inc. ("BioDefense") from CAC for a purchase price consisting of $200,000 in cash and 1,000,000 shares of the Issuer's common stock. After giving effect to the transactions under the SPA, the Issuer owns 80% (16,000,000) of the outstanding shares of BioDefense and CAC owns 20% (4,000,000) of the outstanding shares of BioDefense. Timothy Warbington is the Chairman and Chief Executive Officer of CAC, indirectly owns all of its outstanding shares of capital stock, and beneficially owns the shares held by CAC.
(2)	Amount of shares of the Issuer's common stock beneficially owned following the reported transaction consists of 12,209 shares owned by Timothy Warbington, 1,000,000 shares owned by CAC, and 22,695 shares owned by Creative Medical Health, Inc. ("CMH"). Mr. Warbington is the President of CMH, owns substantially all of its outstanding shares of common stock and beneficially owns the shares held by CMH.

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