Material Event (Form 8-K)

Item 8.01 Other Events.

In the three months ending June 30, 2026, HCW Biologics Inc. ("HCW Biologics" or the "Company") will report a settlement and extinguishment of $2.8 million of disputed accounts payable.

On June 26, 2026, HCW Biologics Inc. received notice that a Voluntary Dismissal with Prejudice had been filed by B&I Contractors, Inc. ("B&I"), which dismissed B&I's crossclaims against the Company in the matter BE&K Building Group, LLC v. HCW Biologics Inc., et al. in the Circuit Court of the 17^th Judicial Circuit in and for Broward County, Florida. The matter originates from B&I filing a mechanics' lien related to unpaid invoices on the Company's property located at 3300 Corporate Way in Miramar, Florida, which is being renovated for future Company offices and laboratories. In addition to the Voluntary Dismissal with Prejudice, B&I filed a final Satisfaction of Lien removing a lien of $1.1 million. The dismissal and lien satisfaction constitute the completion of the settlement agreement between the Company and B&I, thereby fully resolving any and all outstanding amounts owed.

On May 26, 2026, the Company paid in full all amounts owed under a settlement agreement with its contract development and manufacturing organization, EirGenix, Inc. ("EirGenix"), related to manufacturing costs. In the settlement agreement entered into on December 9, 2025, the parties agreed to reduce amounts owed from $1.7 million to $1.2 million if the amount was paid in full by a mutually agreed upon date. The Company paid $620,000 on March 3, 2026, and $620,000 on May 26, 2026. Under the settlement agreement, the Company's obligations to EirGenix were paid in full on May 26, 2026. This completed the satisfaction and resolution of unpaid invoices and disputed credits.

Forward-lookingStatements

This Current Report on Form 8-K contains forward-looking statements. Forward-looking statements may include, but are not limited to, statements related to the expected financial reporting and accounting treatment of the settlements and related obligations, as well as statements, other than historical facts, that address activities, events, or developments that the Company intends, expects, projects, believes, or anticipates will or may occur in the future. These statements are often characterized by terminology such as "believes," "hopes," "may," "anticipates," "should," "intends," "plans," "will," "expects," "estimates," "projects," "positioned," "strategy," and similar expressions and are based on assumptions and assessments made in light of management's experience and perception of historical trends, current conditions, expected future developments, and other factors believed to be appropriate. Forward-looking statements in this Current Report on Form 8-K are made as of the date of this Current Report on Form 8-K, and the Company undertakes no duty to update or revise any such statements, whether as a result of new information, future events, or otherwise. Forward-looking statements are not guarantees of future performance and are subject to risks and uncertainties, many of which are outside of the Company's control. Important factors that could cause actual results, developments, and business decisions to differ materially from forward-looking statements are described in the sections titled "Risk Factors" in the Company's filings with the Securities and Exchange Commission, including its most recent Annual Report on Form 10-K filed on March 31, 2026, as well as Quarterly Reports on Form 10-Q, and Current Reports on Form 8-K..