Management Change/Compensation Form 8 K

Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

Election of Erik Harris as Director

On October 3, 2024, the Board of Directors (the "Board") of Inozyme Pharma, Inc. (the "Company"), following the recommendation of the Nominating and Corporate Governance Committee of the Board, appointed Erik Harris as a director of the Company, effective October 3, 2024. Mr. Harris was designated as a Class II director to serve until the 2025 annual meeting of the stockholders of the Company and thereafter until his successor has been duly elected and qualified, or until his earlier death, resignation or removal.

Mr. Harris has served as the Chief Commercial Officer and Executive Vice President of Ultragenyx Pharmaceutical Inc., a biopharmaceutical company, since June 2019 and served as its Senior Vice President and Head of North American Commercial Operations from July 2017 to June 2019. Prior to Ultragenyx, Mr. Harris spent six years at Crescendo Bioscience, Inc., a molecular diagnostic company, most recently as Vice President of Commercial. Earlier in his career, Mr. Harris served as Vice President of Marketing at InterMune, Inc., a biotechnology company, and also held positions in the commercial organizations at Elan Pharmaceuticals, Inc., Genentech, Inc., and Bristol-Myers Squibb Company. At the start of his professional career, Mr. Harris served as a Lieutenant Commander in Naval Aviation and Congressional Fellow for the United States Navy. Mr. Harris currently serves on the board of directors of Denali Therapeutics Inc., a publicly traded biopharmaceutical company. Mr. Harris received a Master of Business Administration from the Wharton School of Business and a Bachelor of Science from the United States Naval Academy.

Mr. Harris is to be compensated for his service as a director of the Company in the same manner as the Company's other non-employee directors in accordance with the terms of the Company's non-employee director compensation policy, which provides for (i) an annual cash retainer of $40,000 for service as a member of the Board; (ii) an initial option to purchase 56,000 shares of common stock of the Company at an exercise price equal to the closing price per share of the Company's common stock on the Nasdaq Global Select Market on the date of grant and vesting in equal monthly installments over a period of three years; and (iii) following each annual meeting of the Company's stockholders, an option to purchase 28,000 shares of common stock of the Company, vesting on the earlier of the one-year anniversary of the grant date or the next annual meeting of the stockholders.

Mr. Harris has entered into the Company's standard form of indemnification agreement, a copy of which was filed as Exhibit 10.15 to Amendment No. 1 to the Company's Registration Statement on Form S-1 (File No. 333-239648) filed with the Securities and Exchange Commission on July 20, 2020. Pursuant to the terms of this agreement, the Company may be required, among other things, to indemnify Mr. Harris for particular expenses, including attorneys' fees, judgments, fines and settlement amounts incurred by him in any action or proceeding arising out of his service as a director of the Company.

There are no arrangements or understandings between Mr. Harris and any other persons pursuant to which he was selected as a director. Mr. Harris has no family relationships with any of the Company's directors or executive officers. There are no transactions and no proposed transactions between Mr. Harris and the Company that would be required to be disclosed pursuant to Item 404(a) of Regulation S-K of the Securities Act of 1933, as amended.