On January 10, 2025, Aileron Therapeutics, Inc. (the "Company") amended its Restated Certificate of Incorporation, as amended (the "Certificate of Incorporation"), to effect a change of the Company's name from "Aileron Therapeutics, Inc." to "Rein Therapeutics, Inc." (the "Name Change"). The Name Change became effective at 4:00 p.m. Eastern Time on January 10, 2025.

The Board of Directors of the Company (the "Board") approved the Name Change pursuant to Section 242 of the General Corporation Law of the State of Delaware. The Name Change does not affect the rights of the Company's stockholders, and there were no other changes to the Certificate of Incorporation. A copy of the certificate of amendment to the Restated Certificate of Incorporation filed with the Secretary of State of the State of Delaware to affect the Name Change is filed as Exhibit 3.1 and incorporated herein by reference.

In connection with the Name Change, the Board also approved an amendment and restatement of the Company's Amended and Restated Bylaws solely to reflect the Name Change (as amended and restated, the "Amended and Restated Bylaws") effective as of January 10, 2025. A copy of the Amended and Restated Bylaws is filed as Exhibit 3.2 and incorporated herein by reference.