Octenisept® and incorrect use to irrigate deep wounds

Summary and recommendation

Tissue necroses, erythema and persistent oedema are possible adverse drug reactions (unknown frequency) which may occur after irrigation of deep wounds with Octenisept.

Both the medicinal product information ("Warnings and precautions" section, see boxed warning) and the text on the primary packaging state that Octenisept must not be introduced into deep tissue using a syringe and is only intended for topical use (application by swab or spraying).

Despite this warning, cases are still being reported in which irrigation of deep wounds under pressure has led to severe complications with tissue damage.