Cedars-Sinai Experts Present Research at Endocrinology Conference

Cedars-Sinai endocrinologists will share new research and clinical advances at ENDO 2025, the Endocrine Society's annual meeting, July 12-15 in San Francisco.

A pair of Cedars-Sinai investigations highlighted by the Endocrine Society found that people with hypothyroidism are at increased risk for developing small intestinal bacterial overgrowth (SIBO). Excessive levels of certain microbes in the small intestine can cause severe bloating, diarrhea, constipation and nutrient deficiencies.

"We found that the risk for developing SIBO more than doubled in participants with an underactive thyroid. An additional study showed that was especially true if the patients were diagnosed with Hashimoto's disease, also known as autoimmune thyroiditis," said Ruchi Mathur, MD , senior author of the study and a professor of Medicine and director of Clinical Research and Operations in the Medically Associated Science and Technology (MAST) Program at Cedars-Sinai.

Cedars-Sinai experts will be available throughout the meeting for interviews on diabetes, neuroendocrinology, pituitary gland disorders, metabolism, obesity, reproductive endocrinology, insulin regulation and continuous glucose monitoring.

• "Endocrine Society and Pituitary Society Joint Presidential Symposium: Updates in Pituitary Adenomas," a symposium led by Shlomo Melmed, MB, ChB , executive vice president of Medicine and Health Sciences, dean of the Medical Faculty and the Helene A. and Philip E. Hixon Distinguished Chair in Investigative Medicine at Cedars-Sinai.
• "Highlights in Translational and Clinical Neuroendocrinology," an oral presentation, and "Navigating the Complexities and Challenges of Acromegaly Management," a panel discussion, with Laurence Katznelson, MD , vice dean of Medical Education and a distinguished physician-scientist in endocrinology and metabolism.
• "Patients With Hypothyroidism Have a Higher Prevalence of Small Intestinal Bacterial Overgrowth Based on Duodenal Culture, With a Unique Microbial Profile," an oral presentation by Margaret Wei, MD, a Cedars-Sinai fellow. Study senior author is Ruchi Mathur, MD.
• "Local Growth Hormone Triggers Benign Prostate Hyperplasia Development," an oral presentation by Masaki Ryuzaki, MD, PhD, a postdoctoral scientist with the Melmed Lab at Cedars-Sinai. ENDO 2025 Outstanding Abstract Award.
• "Preexisting Diabetes and Pregnancy: Endocrine Society and European Society of Endocrinology Joint Clinical Practice Guidelines," led by Roma Gianchandani, MD , vice chair for Internal Medicine Quality and medical director for Diabetes Quality at Cedars-Sinai.
• "Understanding Acquired Hypothalamic Obesity, a Rare Neuroendocrine Disease," an oral presentation led by Odelia Cooper, MD , associate professor of Medicine and the director of the Clinical and Translational Research Center at Cedars-Sinai.
• "Gut Microbiome and Insulin Homeostasis: The Microbiome and Insulin Longitudinal Evaluation Study (MILES)," a symposium led by Mark O. Goodarzi, MD, PhD , professor of Medicine and Biomedical Sciences, director of the Endocrine Genetics Laboratory, who holds the Eris M. Field Chair in Diabetes Research at Cedars-Sinai.
• "Single-Cell Biology of Pituitary Adenomas," an Endocrine Society and Pituitary Society Joint Presidential Symposium presented by Frederique Ruf-Zamojski, PhD , research associate professor in the Department of Medicine, at Cedars-Sinai.
• "Paracrine GH and the Senescence-Associated Secretory Phenotype,"presented at the Pituitary Society Annual Meeting of the conference by Vera Chesnokova, PhD , research associate professor in the Department of Medicine, at Cedars-Sinai.
• "ATAC Sequencing Analysis Elucidates Novel GHRH-Induced DNA Damage Pathways in Murine Somatotroph," a poster presentation by Deepika Watts, PhD, research associate with the Melmed Lab at Cedars-Sinai. ENDO 2025 Outstanding Abstract Award.
• "Early Biochemical Predictors of Surgical Remission in Patients With Acromegaly," a poster presentation by Dennis Chen, MD , endocrinologist at Cedars-Sinai.

To schedule an interview with a Cedars-Sinai expert, contact Laura Coverson at (310) 562-1112 or [email protected] .