Additional Proxy Soliciting Materials (Form DEFA14A)

Vote at www.ProxyVote.com THIS IS NOT A VOTABLE BALLOT This is an overview of the proposals being presented at the upcoming stockholder meeting. You may view the proxy materials online at www.ProxyVote.com or request a paper or email copy (see reverse side). We encourage you to access and review all of the important information contained in the proxy materials before voting. Please follow the instructions on the reverse side to vote on these important matters. V95725-P50035 1. Election of Directors (each to serve until the 2029 Annual Meeting of Stockholders) For Nominees: Theresa M. Heggie Amy E. McKee, M.D. Jon P. Stonehouse 2. To ratify the appointment of Ernst & Young LLP as the Company's independent registered public accountants for 2026. For 3. To hold a non-binding, advisory vote regarding executive compensation. For 4. To approve an amended and restated Stock Incentive Plan, increasing the number of shares available for issuance under the Stock Incentive Plan. For 5. To transact such other business as may properly come before the meeting or any adjournment thereof. NOTE: UNLESS OTHERWISE SPECIFIED, VALID PROXIES WILL BE VOTED FOR THE ELECTION OF THE PERSONS NOMINATED FOR ELECTION AS DIRECTORS AND FOR PROPOSALS 2, 3 AND 4. IN THEIR DISCRETION, THE PROXY HOLDERS ARE AUTHORIZED TO VOTE UPON SUCH OTHER BUSINESS AS MAY PROPERLY COME BEFORE THE MEETING OR ANY ADJOURNMENT OR POSTPONEMENT THEREOF, SUBJECT TO COMPLIANCE WITH RULE 14A-4(C) OF THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED. Voting Items Board Recommends Prefer to receive an email instead? While voting on www.ProxyVote.com, be sure to click "Delivery Settings."