Statement of Changes in Beneficial Ownership (Form 4)

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b). Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * Foresite Capital Management IV, LLC 2. Issuer Name and Ticker or Trading Symbol Eikon Therapeutics, Inc. [EIKN] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director __X__ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O FORESITE CAPITAL MANAGEMENT, 9200 SUNSET BOULEVARD, SUITE 515 3. Date of Earliest Transaction (Month/Day/Year) 02/04/2026 (Street) WEST HOLLYWOOD, CA 90069 4. If Amendment, Date Original Filed (Month/Day/Year) 6. Individual or Joint/Group Filing (Check Applicable Line) ___ Form filed by One Reporting Person _X_ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 02/04/2026 C(1) 1,340,878 A $ 0 1,340,878 I See Footnote(2) Common Stock 02/04/2026 C(1) 335,521 A $ 0 1,676,399 I See Footnote(2) Common Stock 02/04/2026 C(1) 37,855 A $ 0 1,714,254 I See Footnote(2) Common Stock 02/04/2026 C(1) 229,428 A $ 0 1,943,682 I See Footnote(2) Common Stock 02/04/2026 C(1) 697,885 A $ 0 697,885 I See Footnote(3) Common Stock 02/04/2026 C(1) 37,855 A $ 0 735,740 I See Footnote(3) Common Stock 02/04/2026 C(1) 1,626 A $ 0 737,366 I See Footnote(3) Common Stock 02/04/2026 C(1) 67,207 A $ 0 804,573 I See Footnote(3) Common Stock 02/04/2026 C(1) 458,855 A $ 0 1,263,428 I See Footnote(3) Common Stock 02/04/2026 C(1) 348,942 A $ 0 348,942 I See Footnote(4) Common Stock 02/04/2026 C(1) 37,855 A $ 0 386,797 I See Footnote(4) Common Stock 02/04/2026 C(1) 922 A $ 0 387,719 I See Footnote(4) Common Stock 02/04/2026 C(1) 38,133 A $ 0 425,852 I See Footnote(4) Common Stock 02/04/2026 C(1) 408,725 A $ 0 408,725 I See Footnote(5) Common Stock 02/04/2026 P 55,555 A $18 1,318,983 I See Footnote(3)

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Underlying Securities (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Series A Preferred Stock	(1)	02/04/2026		C(1)			10,000,000	(1)	(1)	Common Stock	1,340,878	$ 0	0	I	See Footnote(2)
Series A-1 Preferred Stock	(1)	02/04/2026		C(1)			2,502,252	(1)	(1)	Common Stock	335,521	$ 0	0	I	See Footnote(2)
Series A-1 Preferred Stock	(1)	02/04/2026		C(1)			5,204,684	(1)	(1)	Common Stock	697,885	$ 0	0	I	See Footnote(3)
Series A-1 Preferred Stock	(1)	02/04/2026		C(1)			2,602,342	(1)	(1)	Common Stock	348,942	$ 0	0	I	See Footnote(4)
Series B-1 Preferred Stock	(1)	02/04/2026		C(1)			282,317	(1)	(1)	Common Stock	37,855	$ 0	0	I	See Footnote(2)
Series B-1 Preferred Stock	(1)	02/04/2026		C(1)			282,317	(1)	(1)	Common Stock	37,855	$ 0	0	I	See Footnote(3)
Series B-1 Preferred Stock	(1)	02/04/2026		C(1)			282,317	(1)	(1)	Common Stock	37,855	$ 0	0	I	See Footnote(4)
Series B-1 Preferred Stock	(1)	02/04/2026		C(1)			3,048,192	(1)	(1)	Common Stock	408,725	$ 0	0	I	See Footnote(5)
Series C Preferred Stock	(1)	02/04/2026		C(1)			12,123	(1)	(1)	Common Stock	1,626	$ 0	0	I	See Footnote(3)
Series C Preferred Stock	(1)	02/04/2026		C(1)			6,878	(1)	(1)	Common Stock	922	$ 0	0	I	See Footnote(4)
Series C-1 Preferred Stock	(1)	02/04/2026		C(1)			501,219	(1)	(1)	Common Stock	67,207	$ 0	0	I	See Footnote(3)
Series C-1 Preferred Stock	(1)	02/04/2026		C(1)			284,392	(1)	(1)	Common Stock	38,133	$ 0	0	I	See Footnote(4)
Series D Preferred Stock	(1)	02/04/2026		C(1)			1,711,025	(1)	(1)	Common Stock	229,428	$ 0	0	I	See Footnote(2)
Series D Preferred Stock	(1)	02/04/2026		C(1)			3,422,051	(1)	(1)	Common Stock	458,855	$ 0	0	I	See Footnote(3)
Warrants	$43.59							02/14/2025	02/14/2030	Common Stock	17,092		17,092	I	See Footnote(2)
Warrants	$43.59							02/14/2025	02/14/2030	Common Stock	34,185		34,185	I	See Footnote(3)

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Foresite Capital Management IV, LLC C/O FORESITE CAPITAL MANAGEMENT 9200 SUNSET BOULEVARD, SUITE 515 WEST HOLLYWOOD, CA 90069		X
Foresite Capital Fund IV, L.P. C/O FORESITE CAPITAL MANAGEMENT 9200 SUNSET BOULEVARD, SUITE 515 WEST HOLLYWOOD, CA 90069		X
Foresite Capital Management V, LLC C/O FORESITE CAPITAL MANAGEMENT 9200 SUNSET BOULEVARD, SUITE 515 WEST HOLLYWOOD, CA 90069		X
Foresite Capital Fund V, L.P. C/O FORESITE CAPITAL MANAGEMENT 9200 SUNSET BOULEVARD, SUITE 515 WEST HOLLYWOOD, CA 90069		X
Foresite Capital Opportunity Management V, LLC C/O FORESITE CAPITAL MANAGEMENT 9200 SUNSET BOULEVARD, SUITE 515 WEST HOLLYWOOD, CA 90069		X
Foresite Capital Opportunity Fund V, L.P. C/O FORESITE CAPITAL MANAGEMENT 9200 SUNSET BOULEVARD, SUITE 515 WEST HOLLYWOOD, CA 90069		X
Foresite Capital VI-A Management, LLC C/O FORESITE CAPITAL MANAGEMENT 9200 SUNSET BOULEVARD, SUITE 515 WEST HOLLYWOOD, CA 90069		X
Foresite Capital VI-A, LLC C/O FORESITE CAPITAL MANAGEMENT 9200 SUNSET BOULEVARD, SUITE 515 WEST HOLLYWOOD, CA 90069		X

Signatures

FORESITE CAPITAL MANAGEMENT IV, LLC, By: /s/ James B. Tananbaum, Managing Member		02/06/2026
**Signature of Reporting Person		Date
FORESITE CAPITAL FUND IV, L.P., By: Foresite Capital Management IV, LLC, Its: General Partner, By: /s/ James B. Tananbaum, Managing Member		02/06/2026
**Signature of Reporting Person		Date
FORESITE CAPITAL MANAGEMENT V, LLC, By: /s/ James B. Tananbaum, Managing Member		02/06/2026
**Signature of Reporting Person		Date
FORESITE CAPITAL FUND V, L.P., By: Foresite Capital Management V, LLC, Its: General Partner, By: /s/ James B. Tananbaum, Managing Member		02/06/2026
**Signature of Reporting Person		Date
FORESITE CAPITAL OPPORTUNITY MANAGEMENT V, LLC, By: /s/ James B. Tananbaum, Managing Member		02/06/2026
**Signature of Reporting Person		Date
FORESITE CAPITAL OPPORTUNITY FUND V, L.P., By: Foresite Capital Opportunity Management V, LLC, Its: General Partner, By: /s/ James B. Tananbaum, Managing Member		02/06/2026
**Signature of Reporting Person		Date
FORESITE CAPITAL VI-A MANAGEMENT, LLC, By: /s/ James B. Tananbaum, Managing Member		02/06/2026
**Signature of Reporting Person		Date
FORESITE CAPITAL VI-A, LLC, By: Foresite Capital VI-A Management, LLC, Its: Managing Member, By: /s/ James B. Tananbaum, Managing Member		02/06/2026
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.
(2)	The shares are held of record by Foresite Capital Fund IV, L.P. ("Fund IV"). Foresite Capital Management IV, LLC ("FCM IV") is the general partner of Fund IV and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM IV, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund IV, disclaims beneficial ownership of the shares held by Fund IV, except to the extent of such person's pecuniary interest in such securities.
(3)	The shares are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund V, disclaims beneficial ownership of the shares held by Fund V, except to the extent of such person's pecuniary interest in such securities.
(4)	The shares are held of record by Foresite Capital Opportunity Fund V, L.P. ("Opportunity Fund V"). Foresite Capital Opportunity Management V, LLC ("FCOM V") is the general partner of Opportunity Fund V and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FCOM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and, other than Opportunity Fund V, disclaims beneficial ownership of the shares held by Opportunity Fund V, except to the extent of such person's pecuniary interest in such securities.
(5)	The shares are held of record by Foresite Capital VI-A, LLC ("Fund VI-A"). Foresite Capital VI-A Management, LLC ("FC VI-A Management") is the general partner of Fund VI-A and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FC VI-A Management, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and, other than Fund VI-A, disclaims beneficial ownership of the shares held by Fund VI-A, except to the extent of such person's pecuniary interest in such securities.

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