Statement of Changes in Beneficial Ownership (Form 4)

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b). Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * PERCEPTIVE ADVISORS LLC 2. Issuer Name and Ticker or Trading Symbol MeiraGTx Holdings plc [MGTX] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director __X__ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 51 ASTOR PLACE, 10TH FLOOR 3. Date of Earliest Transaction (Month/Day/Year) 08/02/2022 (Street) NEW YORK, NY 10003 4. If Amendment, Date Original Filed (Month/Day/Year) 6. Individual or Joint/Group Filing (Check Applicable Line) ___ Form filed by One Reporting Person _X_ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Ordinary Shares 04/17/2026 A 555,555 A $9 10,786,658 I See Footnote(1)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Warrant (Right to Buy)

$15

08/02/2022

A

400,000

08/02/2022

08/02/2027

Ordinary Shares

400,000

(2)

400,000

I

See Footnote(2)

Warrant (Right to Buy)

$20

08/02/2022

A

300,000

08/02/2022

08/02/2027

Ordinary Shares

300,000

(2)

300,000

I

See Footnote(2)

Warrant (Right to Buy)

$15

03/25/2026

D

400,000

08/02/2022

08/02/2027

Ordinary Shares

400,000

(3)

0

I

See Footnote(2)

Warrant (Right to Buy)

$20

03/25/2026

D

300,000

08/02/2022

08/02/2027

Ordinary Shares

300,000

(3)

0

I

See Footnote(2)

Warrant (Right to Buy)

$8

03/25/2026

A

400,000

03/25/2026

08/02/2027

Ordinary Shares

400,000

(3)

400,000

I

See Footnote(2)

Warrant (Right to Buy)

$8

03/25/2026

A

300,000

03/25/2026

08/02/2027

Ordinary Shares

300,000

(3)

300,000

I

See Footnote(2)

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
PERCEPTIVE ADVISORS LLC 51 ASTOR PLACE, 10TH FLOOR NEW YORK, NY 10003	X	X
EDELMAN JOSEPH 51 ASTOR PLACE, 10TH FLOOR NEW YORK, NY 10003	X	X
PERCEPTIVE LIFE SCIENCES MASTER FUND LTD 51 ASTOR PLACE, 10TH FLOOR NEW YORK, NY 10003	X	X

Signatures

/s/ Perceptive Advisors LLC, By: Joseph Edelman, its managing member		04/23/2026
**Signature of Reporting Person		Date
/s/ Joseph Edelman - for Perceptive Life Sciences Master Fund Ltd., By: Perceptive Advisors LLC, its investment manager, By: Joseph Edelman, its managing member		04/23/2026
**Signature of Reporting Person		Date
/s/ Joseph Edelman		04/23/2026
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	The securities are directly held by Perceptive Life Sciences Master Fund Ltd. (the "Master Fund"). Perceptive Advisors LLC (the "Advisor") serves as the investment manager of Master Fund. Joseph Edelman is the managing member of the Advisor. Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.
(2)	Issued to Perceptive Credit Holdings III, LP ("Credit Fund III") in connection with the senior secured financing arrangement (the "Financing Agreement") by and among the Issuer, PCH III, and the other parties thereto. Perceptive Credit Advisors LLC ("Perceptive Credit Advisors") serves as the investment advisor to Credit Fund III and as a relying advisor under the Advisor. Mr. Edelman is the managing member of Perceptive Credit Advisors. Each of Perceptive Credit Advisors, the Advisor and Mr. Edelman disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that any of Perceptive Credit Advisors, the Advisor and Mr. Edelman is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.
(3)	On March 25, 2026, the Issuer, Credit Fund III, and the other parties to the Financing Agreement entered into an agreement whereby the exercise price of the warrants was adjusted to $8.00 per share.
Remarks: Ellen Hukkelhoven, the Head of Investment Research of the Advisor, is a member of the Issuer's board of directors.

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