George Mason researcher receives $1M Community Project Award for a high-resolution mass spectrometer

A new high-resolution mass spectrometer is coming to George Mason University's Center for Molecular Engineering (CME) this fall, thanks to a $1 million Virginia Community Project award given to Mikell Paige, chair of George Mason's Department of Chemistry and Biochemistry in the College of Science.

The Community Project Award was by sponsored by Virginia state representative Suhas Subramanyam (10th District) and emphasizes George Mason's place as one of only four Virginia universities with Carnegie Classification of Institutions of Higher Education's R1 designation. 

The spectrometer, which will be housed at George Mason's Science and Technology Campus, will be instrumental in expanding regional research capacity and workforce training. Curricula utilizing the spectrometer is currently in development.

"I want to thank Congressman Subramanyam and his staff for securing this federal funding. With the mass spectrometer, we can train students in data acquisition and analysis tools," said Paige. "Our center has also been working with local biotechs, government agencies, and other universities. Researchers in these partner facilities rely on us for data analysis, and George Mason students will be able to go into these local industries that require these skillsets after they graduate."

Through the center, Paige has built a robust group of collaborators including institutions, such as Walter Reed National Military Medical Center, National Institutes of Health (NIH), Capital Biosciences, and Amerimmune, and universities, such as Virginia Tech, University of Virginia, Old Dominion University, Georgetown, and the Max Planck Institute in Munich, Germany.

Paige has a background in synthetic chemistry and works in drug discovery, meaning he can synthesize novel, small molecules and design drug molecules as potential medicine. His work has centered on antibacterial and antiviral efforts, and areas such as chronic obstructive pulmonary disease and pulmonary fibrosis-areas where small molecules are necessary for the research process. 

When Paige came to George Mason, he wanted to build a program where he could conduct and expand this research alongside his students. Their work on mass spectrometry prompted their need for the high-resolution component for small molecules. 

"We will also have a continuing education component where local industries could send their companies to come train with our faculty and students to learn how to do the data analysis on their own, as well as provide the core services where they can do a fee-for-service running of samples," said Paige.

"This opportunity makes our center an amazing place for us all to meet other academics and collaborate."

"There is tremendous research and discovery happening right here in our region," said Subramanyam. "I can't wait to see what the mass spectrometer will allow Professor Paige and George Mason students to accomplish as they work toward improving our understanding of medicine."

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