Headlands Research Inc.

06/24/2025 | Press release | Archived content

Once-Monthly Maridebart Cafraglutide for the Treatment of Obesity — A Phase 2 Trial

Christopher Romero, MD, PhD, FACP, Medical Director at Headlands Research and Principal Investigator at Headlands Research Brownsville, collaborated on a phase 2 study evaluating maridebart cafraglutide (MariTide), a novel long-acting peptide-antibody conjugate designed to treat obesity.

The study found that once-monthly administration of MariTide led to substantial and sustained weight reduction in participants with obesity, with or without type 2 diabetes, and favorable effects on glycemic control.

Read the full publication in the New England Journal of Medicine.

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