Statement of Changes in Beneficial Ownership (Form 4)

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b). Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * Miller Lawrence G. 2. Issuer Name and Ticker or Trading Symbol Apnimed, Inc. [APMD] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) APNIMED, INC., 39 JOHN F. KENNEDY STREET, 4TH FLOOR 3. Date of Earliest Transaction (Month/Day/Year) 08/03/2026 (Street) CAMBRIDGE, MA 02138 4. If Amendment, Date Original Filed (Month/Day/Year) 6. Individual or Joint/Group Filing (Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Class A Common Stock 08/03/2026 D(1) 92,431 D (1) 0 I By Lawrence G. Miller Irrevocable Family Trust(2) Common Stock 08/03/2026 A(1) 92,431 A (1) 92,431 I By Lawrence G. Miller Irrevocable Family Trust(2) Common Stock 08/03/2026 C(3) 10,845 A (3) 103,276 I By Lawrence G. Miller Irrevocable Family Trust(2) Class A Common Stock 08/03/2026 D(1) 88,954 D (1) 0 I By Kathleen W. Miller Irrevocable Trust(2) Common Stock 08/03/2026 A(1) 88,954 A (1) 88,954 I By Kathleen W. Miller Irrevocable Trust(2) Class A Common Stock 08/03/2026 D(1) 88,954 D (1) 0 I By James S. Miller Irrevocable Trust(2) Common Stock 08/03/2026 A(1) 88,954 A (1) 88,954 I By James S. Miller Irrevocable Trust(2) Class A Common Stock 08/03/2026 D(1) 88,954 D (1) 0 I By David G. Miller Irrevocable Trust(2) Common Stock 08/03/2026 A(1) 88,954 A (1) 88,954 I By David G. Miller Irrevocable Trust(2) Class A Common Stock 08/03/2026 D(1) 88,954 D (1) 0 I By Ellen K. Williams Irrevocable Family Trust(2) Common Stock 08/03/2026 A(1) 88,954 A (1) 88,954 I By Ellen K. Williams Irrevocable Family Trust(2)

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Underlying Securities (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Series A Preferred Stock	(1)	08/03/2026		C(3)			10,845	(1)	(1)	Common Stock	10,845	$ 0	0	I	By Lawrence G. Miller Irrevocable Family Trust(2)
Stock Option (Right to Buy)	$1	08/03/2026		D(1)			688,042	(4)	01/29/2029	Class A Common Stock	688,042	$ 0	0	D
Stock Option (Right to Buy)	$1	08/03/2026		A(1)		688,042		(4)	01/29/2029	Common Stock	688,042	$ 0	688,042	D
Stock Option (Right to Buy)	$1	08/03/2026		D(1)			98,843	(4)	01/28/2030	Class A Common Stock	98,843	$ 0	0	D
Stock Option (Right to Buy)	$1	08/03/2026		A(1)		98,843		(4)	01/28/2030	Common Stock	98,843	$ 0	98,843	D
Stock Option (Right to Buy)	$1.06	08/03/2026		D(1)			302,541	(4)	03/31/2030	Class A Common Stock	302,541	$ 0	0	D
Stock Option (Right to Buy)	$1.06	08/03/2026		A(1)		302,541		(4)	03/31/2030	Common Stock	302,541	$ 0	302,541	D
Stock Option (Right to Buy)	$2.74	08/03/2026		D(1)			333,580	(4)	06/14/2032	Class A Common Stock	333,580	$ 0	0	D
Stock Option (Right to Buy)	$2.74	08/03/2026		A(1)		333,580		(4)	06/14/2032	Common Stock	333,580	$ 0	333,580	D
Stock Option (Right to Buy)	$4	08/03/2026		D(1)			333,580	(5)	12/22/2032	Class A Common Stock	333,580	$ 0	0	D
Stock Option (Right to Buy)	$4	08/03/2026		A(1)		333,580		(5)	12/22/2032	Common Stock	333,580	$ 0	333,580	D
Stock Option (Right to Buy)	$4.87	08/03/2026		D(1)			333,580	(6)	03/13/2034	Class A Common Stock	333,580	$ 0	0	D
Stock Option (Right to Buy)	$4.87	08/03/2026		A(1)		333,580		(6)	03/13/2034	Common Stock	333,580	$ 0	333,580	D
Stock Option (Right to Buy)	$8.88	08/03/2026		D(1)			59,303	(4)	07/14/2035	Class A Common Stock	59,303	$ 0	0	D
Stock Option (Right to Buy)	$8.88	08/03/2026		A(1)		59,303		(4)	07/14/2035	Common Stock	59,303	$ 0	59,303	D
Stock Option (Right to Buy)	$8.88	08/03/2026		D(1)			25,574	(7)	09/19/2035	Class A Common Stock	25,574	$ 0	0	D
Stock Option (Right to Buy)	$8.88	08/03/2026		A(1)		25,574		(7)	09/19/2035	Common Stock	25,574	$ 0	25,574	D
Stock Option (Right to Buy)	$8.15	08/03/2026		D(1)			74,128	(8)	06/01/2036	Class A Common Stock	74,128	$ 0	0	D
Stock Option (Right to Buy)	$8.15	08/03/2026		A(1)		74,128		(8)	06/01/2036	Common Stock	74,128	$ 0	74,128	D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Miller Lawrence G. APNIMED, INC. 39 JOHN F. KENNEDY STREET, 4TH FLOOR CAMBRIDGE, MA 02138	X

Signatures

/s/Kevin R. Lind, Attorney-in-Fact		08/03/2026
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Pursuant to a reclassification exempt under Rule 16b-7 and Rule 16b-3, each share of Class A Common Stock was reclassified into one share of Common Stock.
(2)	The Reporting Person disclaims beneficial ownership of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of his pecuniary interest therein, if any. This report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 of the Exchange Act or for any other purpose.
(3)	Immediately prior to the Issuer's initial public offering, each share of Series A Preferred Stock automatically converted on a one-for-one basis into shares of the Issuer's Class A Common Stock. The Series A Preferred Stock has no expiration date.
(4)	100% of the shares subject to the option are fully vested.
(5)	25% of the shares subject to such option vest and become exercisable when the Reporting Person completes twelve months of continuous service after December 22, 2022, and the remainder of the shares vest and become exercisable in substantially equal quarterly installments for a period of 36 months thereafter, subject to the Reporting Person's continuous service to the Issuer on each such date.
(6)	25% of the shares subject to such option vest and become exercisable when the Reporting Person completes twelve months of continuous service after December 21, 2023, and the remainder of the shares vest and become exercisable in substantially equal quarterly installments for a period of 36 months thereafter, subject to the Reporting Person's continuous service to the Issuer on each such date.
(7)	25% of the shares subject to such option vest and become exercisable when the Reporting Person completes twelve months of continuous service after September 17, 2025, and the remainder of the shares vest and become exercisable in substantially equal quarterly installments for a period of 36 months thereafter, subject to the Reporting Person's continuous service to the Issuer on each such date.
(8)	The shares subject to such option vest and become exercisable in substantially equal monthly installments for a period of 24 months after June 1, 2026, subject to the Reporting Person's continuous service to the Issuer on each such date.

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