Insight Guru Inc.
10/23/2026 | Press release | Distributed by Public on 10/23/2026 00:12
Market Movers | Winners: TRON, MLTX, EGBN | Losers: AVTX, NVEC, TTMI
The S&P 500 slid 1.2% on Thursday, October 22, while the Nasdaq-100 fell 2.9% and the Dow Jones Industrial Average was flat. Over the past week the S&P 500 is down 1.0%, and over the past month it is down 0.6%.
Gainers outnumbered decliners 2,223 to 1,881 within the Trefis coverage universe. The day's best return belonged to TRON (+21.0%) and the worst to Avalo Therapeutics (AVTX) (-39.2%).
Thursday's Market Winners
The 10 US-listed stocks in the Trefis coverage universe worth at least $300 million with the highest returns on Thursday:
| # | Ticker | Company Name |
1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | TRON | TRON | 21.0% | 21.0% |
| 2 | MLTX | MoonLake Immunotherapeutics | 15.9% | -6.4% |
| 3 | EGBN | Eagle Bancorp | 15.6% | 54.1% |
| 4 | VITL | Vital Farms | 15.2% | -70.5% |
| 5 | FMCC | Federal Home Loan Mortgage | 14.8% | -61.0% |
| 6 | POOL | POOL | 14.4% | -12.1% |
| 7 | HCSG | Healthcare Services | 14.2% | 29.7% |
| 8 | BMI | Badger Meter | 13.5% | -13.4% |
| 9 | AVEX | AEVEX | 13.2% | n/a |
| 10 | FNMA | Federal National Mortgage Association Fannie Mae | 12.6% | -60.8% |
Thursday's Market Losers
And the 10 US-listed stocks in the Trefis coverage universe worth at least $300 million with the lowest returns on Thursday:
| # | Ticker | Company Name |
1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | AVTX | Avalo Therapeutics | -39.2% | -59.0% |
| 2 | NVEC | NVE | -33.7% | 19.3% |
| 3 | TTMI | TTM Technologies | -27.7% | 7.1% |
| 4 | FPS | Forgent Power Solutions | -21.5% | n/a |
| 5 | CRS | Carpenter Technology | -20.6% | -7.0% |
| 6 | VPG | Vishay Precision | -17.9% | 36.9% |
| 7 | MRNA | Moderna | -17.6% | n/a |
| 8 | OII | Oceaneering International | -16.9% | 52.4% |
| 9 | COHU | COHU | -16.3% | 98.8% |
| 10 | MTSI | MACOM Technology Solutions | -15.9% | 34.1% |
Which Of Thursday's Movers Were Already On A Run?
The 39.2% decline in Avalo Therapeutics (AVTX) on Thursday was not a one-off: the stock is down 51.3% over the past month, and down 19.9% over the sessions before Thursday.
Movers Over The Last Week
Widening the window to five trading days, these are the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name |
1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | BRZE | Braze | 51.0% | 33.7% |
| 2 | IRON | Disc Medicine | 32.4% | -5.5% |
| 3 | MYGN | Myriad Genetics | 32.4% | -6.3% |
| 4 | TRON | TRON | 27.7% | 21.0% |
| 5 | TNGX | Tango Therapeutics | 23.0% | 215.2% |
| 6 | XFOR | X4 Pharmaceuticals | 21.2% | -20.0% |
| 7 | NAUT | Nautilus Biotechnology | 20.4% | 33.3% |
| 8 | MANE | Veradermics | 20.4% | n/a |
| 9 | MLTX | MoonLake Immunotherapeutics | 20.3% | -6.4% |
| 10 | DFH | Dream Finders Homes | 19.9% | -40.8% |
Losers
| # | Ticker | Company Name |
1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | AVTX | Avalo Therapeutics | -38.0% | -59.0% |
| 2 | NVEC | NVE | -34.1% | 19.3% |
| 3 | SECZ | Securitize | -29.7% | n/a |
| 4 | AVEX | AEVEX | -27.8% | n/a |
| 5 | TTMI | TTM Technologies | -27.1% | 7.1% |
| 6 | CBRS | Cerebras Systems | -23.4% | n/a |
| 7 | CRS | Carpenter Technology | -23.2% | -7.0% |
| 8 | FPS | Forgent Power Solutions | -23.0% | n/a |
| 9 | FLEX | FLEX | -22.1% | 26.9% |
| 10 | NVAX | Novavax | -22.1% | 48.7% |
Movers Over The Last Month
And over the last 21 trading days, the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name |
1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | NAUT | Nautilus Biotechnology | 172.6% | 33.3% |
| 2 | BMBL | Bumble | 121.6% | 66.4% |
| 3 | BRZE | Braze | 77.3% | 33.7% |
| 4 | FIGS | FIGS | 70.9% | 80.1% |
| 5 | DXC | DXC Technology | 47.8% | 9.8% |
| 6 | PCRX | Pacira BioSciences | 47.5% | 40.4% |
| 7 | PACB | Pacific Biosciences of California | 46.1% | 10.2% |
| 8 | RXO | RXO | 45.5% | 128.8% |
| 9 | KSS | Kohl's | 45.4% | 24.4% |
| 10 | MYGN | Myriad Genetics | 43.6% | -6.3% |
Losers
| # | Ticker | Company Name |
1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | EMAT | Evolution Metals & Technologies | -59.5% | n/a |
| 2 | CIFR | Cipher Digital | -54.7% | -43.6% |
| 3 | EOSE | Eos Energy Enterprises | -52.2% | -85.1% |
| 4 | AVTX | Avalo Therapeutics | -51.3% | -59.0% |
| 5 | FMC | FMC | -48.8% | -63.1% |
| 6 | RIOT | Riot Platforms | -47.8% | 1.7% |
| 7 | CBRS | Cerebras Systems | -46.9% | n/a |
| 8 | PCT | PureCycle Technologies | -46.0% | -67.6% |
| 9 | QURE | uniQure | -46.0% | -3.4% |
| 10 | MARA | MARA | -45.7% | -19.3% |
Today's Winner Is Tomorrow's Loser Often Enough
The movers list is the most honest picture of single-stock risk the market prints each day: the same volatility that makes the winners column also fills the losers column, and no one reliably knows which side a stock lands on next.
That is the case for owning a disciplined basket instead of chasing the tape. The Trefis High Quality (HQ) Portfolio holds roughly 30 businesses selected for consistent cash generation, strong margins, and resilient balance sheets, sized and rebalanced with rules. It has a track record of outpacing a benchmark that combines the S&P 500, the S&P MidCap 400, and the Russell 2000. Watch the movers for information; let the portfolio do the compounding.
Insight Guru Inc. published this content on October 23, 2026, and is solely responsible for the information contained herein. Distributed via Public Technologies (PUBT), unedited and unaltered, on October 23, 2026 at 06:14 UTC. If you believe the information included in the content is inaccurate or outdated and requires editing or removal, please contact us at [email protected]