Statement of Changes in Beneficial Ownership (Form 4)

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b). Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person * Bohnen Shane 2. Issuer Name and Ticker or Trading Symbol BIO-TECHNE Corp [TECH] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) SVP - General Counsel (Last) (First) (Middle) 614 MCKINLEY PLACE NE 3. Date of Earliest Transaction (Month/Day/Year) 04/03/2026 (Street) MINNEAPOLIS, MN 55413 4. If Amendment, Date Original Filed (Month/Day/Year) 6. Individual or Joint/Group Filing (Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 04/03/2026 M 2,259 A $ 0 6,644 D Common Stock 04/03/2026 F 740 D $53.13 5,904 D

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Underlying Securities (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (Right to Buy)	$47.6							(1)	08/07/2026	Common Stock	8,848		8,848	D
Stock Option (Right to Buy)	$66.97							(1)	08/05/2027	Common Stock	8,944		8,944	D
Stock Option (Right to Buy)	$120.46							(1)	08/06/2028	Common Stock	3,460		3,460	D
Stock Option (Right to Buy)	$94.52							(2)	08/15/2029	Common Stock	3,508		3,508	D
Stock Option (Right to Buy)	$73.76							(3)	04/03/2030	Common Stock	3,928		3,928	D
Restricted Stock Units	(4)	04/03/2026		M			2,259	(5)	(5)	Common Stock	2,259	$ 0	0	D
Stock Option (Right to Buy)	$84.61							(6)	08/15/2030	Common Stock	16,302		16,302	D
Restricted Stock Units	(4)							(7)	(7)	Common Stock	49		49	D
Performance Restricted Stock Units	(4)							(8)	(8)	Common Stock	4,802		4,802	D
Performance Stock Option (Right to Buy)	$84.61							(8)	(8)	Common Stock	12,924		12,924	D
Performance Restricted Stock Units	(4)							(9)	(9)	Common Stock	10,012		10,012	D
Restricted Stock Units	(4)							(10)	(10)	Common Stock	3,338		3,338	D
Stock Option (Right to Buy)	$74.91							(11)	08/15/2034	Common Stock	13,488		13,488	D
Performance Restricted Stock Units	(4)							(12)	(12)	Common Stock	13,992		13,992	D
Restricted Stock Units	(4)							(13)	(13)	Common Stock	6,996		6,996	D
Stock Option (Right to Buy)	$53.6							(14)	08/15/2035	Common Stock	17,897		17,897	D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Bohnen Shane 614 MCKINLEY PLACE NE MINNEAPOLIS, MN 55413			SVP - General Counsel

Signatures

/s/ Shane Bohnen		04/07/2026
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Fully exercisable.
(2)	Options to purchase 876 shares vest on each of 8/15/2023, 8/15/2025 and 8/15/2026, and options to purchase 880 shares vest on 8/15/2024.
(3)	Options to purchase 982 shares vest on each of 4/3/2024, 4/3/2025, 4/3/2026 and 4/3/2027.
(4)	Each restricted stock unit represents a contingent right to receive one share of Bio-Techne common stock.
(5)	2,259 restricted stock units vest on 4/3/2026.
(6)	Options to purchase 4,076 shares vest on 8/15/2024 and 8/15/2026, and options to purchase 4,075 shares vest on 8/15/2025 and 8/15/2027.
(7)	49 restricted stock units vest on 8/15/2026.
(8)	Vests in full or in part on 8/15/2026 if certain performance goals are achieved (or such later date as performance is certified by the Administrator).
(9)	Vests in full or in part on 8/15/2027 if certain performance goals are achieved (or such later date as performance is certified by the Administrator).
(10)	1,669 restricted stock units vest on each of 8/15/2026 and 8/15/2027.
(11)	Options to purchase 3,372 shares vest on each of 8/15/2025, 8/15/2026, 8/15/2027 and 8/15/2028.
(12)	Vests in full or in part on 8/15/2028 if certain performance goals are achieved (or such later date as performance is certified by the Administrator).
(13)	2,332 restricted stock units vest on each of 8/15/2026, 8/15/2027 and 8/15/2028.
(14)	Options to purchase 5,966 shares vest on each of 8/15/2026 and 8/15/2027, and options to purchase 5,965 shares vest on 8/15/2028.

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