Ascension Health Alliance

04/09/2026 | Press release | Distributed by Public on 04/09/2026 12:19

Ascension Saint Thomas physicians warn of rising colorectal cancer cases in younger adults

Physicians with Ascension Saint Thomas are raising concerns about a growing trend across Middle Tennessee and the United States. Younger adults are receiving colorectal cancer diagnoses more often without realizing they are at risk.

Colorectal cancer is now the deadliest cancer for Americans younger than 50, according to research published in JAMA. New data from the American Cancer Society shows nearly half of new cases occur in adults younger than 65, with one in five diagnosed before age 55. Researchers also found people born in 1990 are twice as likely to develop colon cancer and four times more likely to develop rectal cancer than those born in 1950.

In Tennessee, about 3,500 people receive a colorectal cancer diagnosis each year, making it one of the most common cancers in the state. In many cases, physicians diagnose colorectal cancer at a more advanced stage.

"Colorectal cancer is the fastest growing cancer in people under 50," said Dr. Brett Inglis, a gastroenterologist with Ascension Saint Thomas. "We are unfortunately seeing this cancer even in 35 year olds. That was uncommon a decade ago. The reason for this sudden rise is not fully understood, and there are many ongoing investigations to find the cause."

Physicians say several factors may contribute to the increase, including smoking, diet, lifestyle, obesity and changes in the gut microbiome.

"Colorectal cancer screening rates vary by state, reaching only two thirds of the population nationally," Inglis said. "The best test is the one that gets done. People should talk with their primary care doctor about getting screened, as colorectal cancer is the most preventable cancer."

Screening methods include colonoscopy and at-home stool based tests. When detected early, colorectal cancer has a significantly higher survival rate.

Doctors urge people to pay attention to warning signs, which may include:

  • Changes in bowel habits
  • Blood in the stool
  • Persistent abdominal pain
  • Unexplained weight loss
  • Fatigue

"This cancer is very preventable and should not be the second leading cause of cancer death in our nation," Inglis said. "Early detection can save lives."

The U.S. Preventive Services Task Force recommends adults at average risk begin colorectal cancer screening at age 45. People with a family history or other risk factors may need to start earlier and should have screenings every five years.

Ascension Saint Thomas encourages Middle Tennessee residents to talk with their doctor about their risk and when to begin screening. To learn more about colon cancer screening in Middle Tennessee, visit Ascension Saint Thomas online.

Ascension Health Alliance published this content on April 09, 2026, and is solely responsible for the information contained herein. Distributed via Public Technologies (PUBT), unedited and unaltered, on April 09, 2026 at 18:19 UTC. If you believe the information included in the content is inaccurate or outdated and requires editing or removal, please contact us at [email protected]