Proxy Statement (Form 8-K)

Item 5.08 Shareholder Director Nominations.

Adagio Medical Holdings, Inc. (the "Company") has set June 16, 2026 as the date of the Company's 2026 Annual Meeting of Stockholders (the "2026 Annual Meeting"). The time and location of the 2026 Annual Meeting will be set forth in the Company's definitive proxy statement for the 2026 Annual Meeting to be filed with the Securities and Exchange Commission (the "SEC"). The record date for determining stockholders entitled to notice of, and to vote at, the 2026 Annual Meeting will be the close of business on April 24, 2026.

Stockholders who intend to present proposals for inclusion in the Company's proxy materials for the 2026 Annual Meeting pursuant to Rule 14a-8 ("Rule 14a-8") promulgated under the Securities and Exchange Act of 1934, as amended (the "Exchange Act"), must ensure that such proposals are delivered to or mailed and received by the Company's Secretary at Adagio Medical Holdings, Inc., 26051 Merit Circle, Suite 102 Laguna Hills, CA, no later than April 30, 2026, which the Company has determined to be a reasonable time before it expects to begin to deliver and make available its proxy materials for the 2026 Annual Meeting, and must furthermore comply with all applicable requirements of Rule 14a-8.

Pursuant to the Company's amended and restated bylaws ("Bylaws"), for stockholder director nominations or other proposals to be considered at an annual meeting, the stockholder must give timely notice thereof in writing to the Company's Secretary at Adagio Medical Holdings, Inc., 26051 Merit Circle, Suite 102 Laguna Hills, CA, no later than the 10th day following the day on which public announcement of the date of such meeting was first made. To be timely for the 2026 Annual Meeting, a stockholder's notice must be delivered to or mailed and received by the Company's Secretary at the Company's principal executive offices not later than April 30, 2026, the tenth calendar day following the date of this Current Report on Form 8-K publicly announcing the date of the 2026 Annual Meeting. A stockholder's notice to the Secretary must also set forth the information required by the Bylaws.

In addition to satisfying the foregoing requirements under the Bylaws, to comply with the SEC's universal proxy rules, stockholders who intend to solicit proxies in support of director nominees other than the Company's nominees must provide notice to the Company that sets forth the information required by Rule 14a-19 under the Exchange Act no later than April 30, 2026.