Material Agreement (Form 8-K)

Item 1.01. Entry into a Material Definitive Agreement.

On August 12, 2026, iSpecimen Inc. (the "Company") entered into a Consulting Agreement (the "Consulting Agreement") with IR Agency LLC (the "Consultant"), pursuant to which the Consultant agreed to provide marketing and advertising services designed to communicate information about the Company to the financial community, including the creation of company profiles and media distribution.

The Consulting Agreement provides for a three-month term commencing on August 12, 2026, during which the Consultant will provide marketing and news distribution services for a maximum of ten news releases. The Consultant will act as an independent contractor, and the services provided under the Consulting Agreement are non-exclusive.

In consideration for the services to be provided under the Consulting Agreement, the Company agreed to pay the Consultant an aggregate cash fee of $2,000,000 by August 13, 2026. The fee is fully earned upon receipt and is non-refundable. The Company may request that the term be extended for months during which no news distribution services are performed, and any additional or out-of-scope services will be subject to separate compensation arrangements.

Either party may terminate the Consulting Agreement, with or without cause, at any time upon written notice to the other party. If the Company terminates the Consulting Agreement during the initial term for any reason, the Company will not be entitled to a refund of any portion of the compensation paid. The Consultant may immediately suspend or terminate the services if it believes continued performance may expose it to legal, regulatory or reputational risk, in which case no refund will be owed.

The Consultant has agreed that it will not solicit orders, make investment recommendations, provide investment advice or effect securities transactions, and that it will comply in all material respects with applicable U.S. securities laws in performing the services. The Consulting Agreement also contains provisions relating to the accuracy and approval of Company information and promotional materials, paid-promotion disclosures, confidentiality and material non-public information, indemnification by the Company, limitations of the Consultant's liability and binding arbitration in New Jersey.

The foregoing description of the Consulting Agreement does not purport to be complete and is qualified in its entirety by reference to the full text of the Consulting Agreement, which is filed as Exhibit 10.1 to this Current Report on Form 8-K and incorporated herein by reference.