Material Agreement (Form 8-K)

On July 28, 2026, Aldeyra Therapeutics, Inc. ("Aldeyra" or the "Company") executed a lease agreement (the "Office Lease") with Bradford Street, L.L.C. ("Bradford Street") for approximately 4,067 square feet of office space located at 23 Bradford Street, Concord, Massachusetts (the "Premises"). The Office Lease commences on September 1, 2026 and the term with respect to the Premises shall be for a period ending on September 30, 2029. The Company intends to use the Premises as its corporate headquarters. The Office Lease provides for a monthly base rent of $12,201.00, increasing each year as indicated in the Office Lease (the "Base Rent"). In addition to the Base Rent, the Company is required to pay Bradford Street certain operating expenses, taxes, and other fees in accordance with the terms of the Office Lease. The Office Lease contains customary representations and covenants regarding occupancy, maintenance, and care of the Premises. The Company will post an initial security deposit in the amount of $50,000.00.

The foregoing description of the Office Lease does not purport to be complete and is qualified in its entirety by the full text of the Office Lease, a copy of which is filed as Exhibit 10.1 to this Current Report on Form 8-K and is incorporated by reference herein.