Bruker Introduces Innovative Ascend Evo 700 and 800 Magnets

ASILOMAR, California- April 5, 2025 - At the Joint ENC-ISMAR Conference 2025, Bruker Corporation announced the launch of its latest innovations in the Ascend Evo™ NMR superconducting magnet series, the new Ascend Evo 700 and 800. These new magnets are designed to expand access to high-field NMR, with enhanced sustainability for the scientific research and biopharma community.

Building on the success of the Ascend Evo series, which includes compact 400, 500 and 600 MHz magnets, plus the unique 1.0 GHz magnet, the new Ascend Evo 700 and 800 MHz 54mm magnets are more compact, lighter, and consume significantly less helium than previous high-field magnets. Their weight is reduced by 33% and 20%, respectively, while helium consumption is reduced by 40% at 700 MHz, and by 33% at 800 MHz. This results in increased helium hold times of 240 and 180 days for the new Ascend Evo 700 and 800 magnets, respectively.

Bruker's proprietary, cryogenically cooled shim technology ensures further improved field homogeneity, with optimized shimming now implemented in the factory so that only minimal adjustments are required during installation at the customer site. This translates into shorter settling times, allowing virtually immediate customer use, and maximizes uptime with rock-steady long-term homogeneity. The Ascend Evo magnets retain all well-known benefits of the Ascend series, including minimal field drift and stray field, and exceptional 99% screening against external disturbances. The Ascend Evo 800 is a 5^th-generation 800 magnet, now spanning three decades of technological advancements.

"With the introduction of the Ascend Evo 700 and 800 magnets, we are taking significant strides in making high-field NMR more accessible," said Falko Busse, President of the Bruker BioSpin Group. "These innovations allow our customers to conduct remarkable high-field NMR research in standard labs, due to reduced footprint, lower helium consumption, and improved magnetic field homogeneity."

At ENC-ISMAR 2025, Bruker also announced an expanded roadmap for ultra-sensitive solid-state NMR at 1.0 GHz: this includes 3.2mm HCN and HX CP/MAS CryoProbes, and solid-state Dynamic Nuclear Polarization (DNP) 1.3mm CP/MAS probes for standard-bore (SB) 1.0 GHz magnets, as well as the pending development of new gyrotron microwave sources for DNP at 1.0 or 1.2 GHz. MAS CryoProbes and SB DNP probes are already available at 600 - 800 MHz, where sensitivity gains up to 10x have been achieved for MAS CryoProbes, and up to 200x for solid-state DNP NMR.

MAS CryoProbes are applicable to unmodified samples at or near ambient temperatures, for a broad range of sample types from pharmaceuticals to biological systems, and diverse new materials.

DNP requires specialized sample preparation and low-temperature (100 K) operation, where one or two orders of magnitude sensitivity gains can enable previously impossible research, including the characterization of buried surfaces and interfacial layers in materials science, and protein-protein interactions within live cells for biological sciences.

Bringing MAS CryoProbe and DNP gains to Ascend Evo 1.0 GHz systems enables applications with even higher spectral resolution, resulting in unparalleled interrogation capabilities for critical problems in biomolecular systems, advanced materials and biopharmaceutical sciences.