08/14/2025 | Press release | Distributed by Public on 08/13/2025 22:18
NCHS Data Brief No. 537, August 2025
PDF Version (369 KB)
Anjel Vahratian, Ph.D., M.P.H., and Antonia Warren, M.S.
Data from the National Health Interview Survey
Glucagon-like peptide-1 (GLP-1) receptor agonists are a type of drug that mimics a hormone in the body which helps to lower blood sugar and support weight loss (1). GLP-1 medications are typically administered as an injection to treat type 2 diabetes (1). This report describes the percentage of adults with diagnosed diabetes who were taking an injectable GLP-1 medication at the time of interview by selected characteristics, based on data from the 2024 National Health Interview Survey (NHIS). Survey respondents were assumed to be using a GLP-1 injectable if they had diabetes and reported use of an injectable medication other than insulin to lower blood sugar or lose weight.
Keywords: incretin mimetics; glycemic control; semaglutide; dulaglutide; National Health Interview Survey (NHIS)
| Selected characteristic | Percent (95% confidence interval) | Standard error |
| Total | 26.5 (24.7-28.5) | 0.97 |
| Sex | ||
| Men | 25.9 (23.1-28.7) | 1.41 |
| Women | 27.2 (24.8-29.8) | 1.26 |
| Age group | ||
| 18-34 | 125.3 (13.7-40.2) | 6.39 |
| 35-49 | 29.7 (24.4-35.4) | 2.74 |
| 50-64 | 33.3 (29.9-36.9) | 1.74 |
| 65 and older | 20.8 (18.5-23.4) | 1.22 |
1Significant quadratic trend by age (p < 0.05). Pairwise tests indicate significant differences between those ages 35-49 and 50-64 compared with those age 65 and older.
NOTES: The total percentage of 26.5% is equal to an estimated 6.9 million adults with diagnosed diabetes who used glucagon-like peptide-1 (GLP-1) injectables in 2024. Estimates are based on household interviews of a sample of the U.S. civilian noninstitutionalized population.
SOURCE: National Center for Health Statistics, National Health Interview Survey, 2024.
| Selected characteristic | Percent (95% confidence interval) | Standard error |
| Race and Hispanic origin | ||
| Asian, non-Hispanic | 112.1 (7.2-18.7) | 2.77 |
| Black, non-Hispanic | 26.5 (21.4-32.2) | 2.66 |
| White, non-Hispanic | 26.2 (24.0-28.3) | 1.09 |
| Hispanic | 31.3 (25.6-37.5) | 2.94 |
| Family income | ||
| Less than 100% FPL | 25.8 (20.9-31.2) | 2.55 |
| 100% to less than 200% FPL | 24.2 (20.2-28.6) | 2.09 |
| 200% to less than 400% FPL | 26.2 (22.8-29.9) | 1.79 |
| 400% FPL or more | 29.0 (25.8-32.4) | 1.65 |
1Significantly lower than Black non-Hispanic, White non-Hispanic, and Hispanic adults with diagnosed diabetes (p < 0.05).
NOTES: GLP-1 is glucagon-like peptide-1. Categories shown for non-Hispanic adults are for those who selected only one racial group. Adults categorized as Hispanic may be of any race or combination of races. FPL is federal poverty level. Estimates are based on household interviews of a sample of the U.S. civilian noninstitutionalized population.
SOURCE: National Center for Health Statistics, National Health Interview Survey, 2024.
| Body mass index | Percent (95% confidence interval) | Standard error |
| Underweight | * | * |
| Healthy weight | 116.7 (12.9-21.0) | 2.00 |
| Overweight | 22.2 (19.1-25.5) | 1.60 |
| Obesity | 32.4 (29.7-35.1) | 1.34 |
* Estimate does not meet National Center for Health Statistics standards of reliability.
1Significant increasing linear test of trend (p < 0.05).
NOTES: GLP-1 is glucagon-like peptide-1. Underweight is body mass index (BMI) of less than 18.5 kg/m2. Healthy weight is BMI of 18.5 to less than 25.0 kg/m2. Overweight is BMI of 25.0 to less than 30.0 kg/m2. Obesity is BMI of 30.0 kg/m2 or more. Estimates are based on household interviews of a sample of the U.S. civilian noninstitutionalized population.
SOURCE: National Center for Health Statistics, National Health Interview Survey, 2024.
| Diabetes medication use | Percent (95% confidence interval) | Standard error |
| Insulin | ||
| Yes | 131.3 (28.1-34.6) | 1.64 |
| No | 24.5 (22.2-26.9) | 1.19 |
| Oral glucose-lowering medications | ||
| Yes | 128.1 (25.8-30.5) | 1.20 |
| No | 22.2 (19.1-25.6) | 1.63 |
1Significantly different from adults with diagnosed diabetes who did not take that medication (p < 0.05).
NOTES: GLP-1 is glucagon-like peptide-1. Estimates are based on household interviews of a sample of the U.S. civilian noninstitutionalized population.
SOURCE: National Center for Health Statistics, National Health Interview Survey, 2024.
In 2024, 26.5% of adults with diagnosed diabetes used GLP-1 injectables to lower blood sugar or lose weight. One in three adults ages 50-64 (33.3%) used GLP-1 injectables, and use was more common among adults with higher BMIs. In recent years, public awareness and use of GLP-1 medications has rapidly grown (2,3). An analysis of data from the Medical Expenditure Panel Survey showed a 155% increase in the percentage of adults with type 2 diabetes who used GLP-1 injectables from 2018 (7.6%) to 2022 (19.4%) (2). Concurrently, spending on GLP-1 medications increased by more than 500% from 2018 to 2023, based on data from retail and mail-order prescription fills (4).
Body mass index (BMI): Based on responses to the following two survey questions: "How tall are you without shoes?" and "How much do you weigh?" Data from these two questions are used to compute a BMI measure in kilograms divided by meters squared. BMI classifications are: underweight, BMI less than 18.5; healthy weight, BMI of 18.5 to less than 25.0; overweight, BMI of 25.0 to less than 30.0; and obesity, BMI of 30.0 or more (5).
Glucagon-like peptide-1 (GLP-1) injectable use: Based on a yes response to the survey question, "Other than insulin, are you taking any injectable medications to lower your blood sugar or lose weight?" The survey included the following statement that could be read by interviewers if needed: "These medications include GLP-1 injectables, such as Ozempic, Wegovy, Saxenda, Victoza, Trulicity, Mounjaro, and Byetta."
Race and ethnicity: Adults categorized as Hispanic may be of any race or combination of races. Non-Hispanic adults categorized as Asian, Black, or White indicated one race only. Estimates for non-Hispanic adults of races other than Asian, Black, and White are not shown due to the inability to make statistically reliable estimates for these groups, but they are included in total estimates.
Data from the 2024 NHIS were used for this analysis. NHIS is a nationally representative household survey of the U.S. civilian noninstitutionalized population. It is conducted continuously throughout the year by the National Center for Health Statistics. Interviews are typically initiated face-to-face in respondents' homes, but follow-ups to complete interviews may be conducted over the telephone (6). For more information on the survey, visit the NHIS website: https://www.cdc.gov/nchs/nhis/index.htm.
Point estimates and the corresponding confidence intervals for this analysis were calculated using SAS-callable SUDAAN software (7) to account for the complex sample design of NHIS. All estimates are based on self-report and meet National Center for Health Statistics data presentation standards for proportions (8). Differences between percentages were evaluated using two-sided significance tests at the 0.05 level. Linear and quadratic trends by age group, family income, and BMI were evaluated using orthogonal polynomials.
Anjel Vahratian and Antonia Warren are with the National Center for Health Statistics, Division of Health Interview Statistics.
Vahratian A, Warren A. GLP-1 injectable use among adults with diagnosed diabetes: United States, 2024. NCHS Data Brief. 2025 Aug;(537):1-8. DOI: https://dx.doi.org/10.15620/cdc/174616.
All material appearing in this report is in the public domain and may be reproduced or copied without permission; citation as to source, however, is appreciated.
Brian C. Moyer, Ph.D., Director
Amy M. Branum, Ph.D., Associate Director for Science
Stephen J. Blumberg, Ph.D., Director
Anjel Vahratian, Ph.D., M.P.H., Associate Director for Science