NIST - National Institute of Standards and Technology

10/05/2026 | Press release | Distributed by Public on 10/06/2026 03:09

On Methods of Uncertainty Quantification in Computational Modeling and Simulation: Harmonizing Modeling and Metrology Practices

Published
October 5, 2026

Author(s)

Vijay Srinivasan

Abstract

As Computational Modeling and Simulation (CMS) increasingly drives critical engineering and regulatory decisions, establishing model credibility has become paramount. This report presents a comprehensive approach to harmonizing the uncertainty quantification (UQ) methods within the computational modeling standards of the American Society of Mechanical Engineers (ASME) with the empirical metrology practices of the Joint Committee for Guides in Metrology (JCGM). We explain a standardized, risk-based approach to credibility assessment, demonstrating how Verification, Validation, and Uncertainty Quantification (VVUQ) efforts can be scaled in proportion to model risk, which is determined by model influence and decision consequence. To navigate the modern CMS landscape, we categorize models across creation, logic, and transparency perspectives, contrasting mechanistic first-principles approaches with empirical data-driven techniques. Furthermore, this work details the mathematical methods of UQ, comparing the propagation of variances against the propagation of distributions, and highlights recent developments in the physical interpretation of adjoint methods to overcome computational bottlenecks in sensitivity analysis. Finally, we look ahead to the challenges of UQ in Artificial Intelligence (AI) models and the integration of UQ practices into digital twin ecosystems and industrial ontologies. Ultimately, this work provides a unified framework for bridging the gap between computational predictions and physical reality.
Citation
NIST Advanced Manufacturing Series: Reports Subseries - 100-85
Report Number
100-85
Pub Type
NIST Pubs

Keywords

Adjoint Methods, Computational Modeling and Simulation (CMS), Credibility Assessment, Digital Twins, Metrology, Ontologies, Risk-Based Framework, Sensitivity Analysis, Uncertainty Quantification (UQ), Verification and Validation (V&V).

Citation

Srinivasan, V. (2026), On Methods of Uncertainty Quantification in Computational Modeling and Simulation: Harmonizing Modeling and Metrology Practices, NIST Advanced Manufacturing Series: Reports Subseries, National Institute of Standards and Technology, Gaithersburg, MD, [online], https://doi.org/10.6028/NIST.AMS.100-85, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=962918 (Accessed October 6, 2026)
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NIST - National Institute of Standards and Technology published this content on October 05, 2026, and is solely responsible for the information contained herein. Distributed via Public Technologies (PUBT), unedited and unaltered, on October 06, 2026 at 09:09 UTC. If you believe the information included in the content is inaccurate or outdated and requires editing or removal, please contact us at [email protected]