Proxy Results, Management Change/Compensation (Form 8-K)

Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

On June 11, 2025, Trevi Therapeutics, Inc., a Delaware corporation (the "Company"), held its 2025 Annual Meeting of Stockholders (the "Annual Meeting"). At the Annual Meeting, the Company's stockholders, upon the recommendation of the Board of Directors of the Company (the "Board"), approved an amendment to the Company's 2019 Stock Incentive Plan (the "2019 Plan"), which amendment had previously been approved by the Board subject to stockholder approval, to increase the number of shares available for issuance under the plan by 6,000,000 shares of common stock and make certain other amendments.

The description of the amendment to the 2019 Plan contained in the Company's definitive proxy statement for the Annual Meeting, filed with the Securities and Exchange Commission (the "SEC") on April 29, 2025 (the "Proxy Statement"), under the heading "Proposal No. 5-Approval of an Amendment to the Trevi Therapeutics, Inc. 2019 Stock Incentive Plan" is incorporated herein by reference. A complete copy of the amendment to the 2019 Plan is attached as Exhibit 99.1 hereto and is incorporated herein by reference.

Item 5.07 Submission of Matters to a Vote of Security Holders

On June 11, 2025, the Company held the Annual Meeting. At the Annual Meeting, the Company's stockholders voted on the following proposals:

1. The following nominees were elected to the Board as Class III directors for terms expiring at the 2028 annual meeting of stockholders.

2. The appointment of Ernst & Young LLP as the independent registered public accounting firm for the Company for the fiscal year ending December 31, 2025 was ratified.

3. The compensation of the Company's named executive officers was approved, on an advisory basis.

4. The Company's stockholders recommended, on an advisory basis, that future advisory votes to approve the compensation paid to the Company's named executive officers be held every year.

After taking into consideration the foregoing voting results and the prior recommendation of the Board in favor of an annual stockholder advisory vote on the compensation of the Company's named executive officers, the Company currently intends to hold future advisory votes on the compensation of the Company's named executive officers every year.

5. The amendment to the 2019 Plan to increase the number of shares available for issuance under the plan by 6,000,000 shares of common stock, and make certain other amendments, was approved.