12/19/2025 | Press release | Distributed by Public on 12/19/2025 07:26
| Item 8.01. |
Other Events. |
On December 19, 2025, Spero Therapeutics, Inc. (the "Company") announced that its tebipenem HBr development partner, GlaxoSmithKline Intellectual Property (No. 3) Limited ("GSK"), filed a New Drug Application ("NDA") resubmission to the U.S. Food and Drug Administration for tebipenem HBr, an investigational oral carbapenem antibiotic being developed for the treatment of complicated urinary tract infections (cUTI), including pyelonephritis. The NDA submission triggers a $25 million milestone payment to the Company under the Company's License Agreement, as amended, with GSK, which is expected to be received in the first quarter of 2026.