J. Craig Venter Institute Inc.
02/18/2026 | Press release | Archived content
Divergent Patterns of Genetic Overlap Between Severe Mental Disorders and Metabolic Markers
The American journal of psychiatry. 2026-02-18; appiajp20250259.
Divergent Patterns of Genetic Overlap Between Severe Mental Disorders and Metabolic Markers
van der Meer D, Shadrin AA, Stinson SE, Koch E, Rokicki J, Rahman Z, Bergstedt J, Ottas A, Sønderby IE, Rødevand L, Fuhrer J, Quintana DS, Dale AM, O'Connell KS, Djurovic S, Lehto K, Milani L, Alver M, Andreassen OA
PMID: 41703690
Abstract
Bipolar disorder, major depressive disorder (MDD), and schizophrenia are severe mental disorders and are each associated with poor cardiometabolic health. Mapping genetic relationships of these heritable disorders with blood markers of metabolic activity may uncover biological pathways underlying this important shared clinical feature.
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