Insight Guru Inc.

09/04/2026 | Press release | Distributed by Public on 09/04/2026 04:21

Market Movers | Winners: CYPH, ABTC, MRLN | Losers: RARE, MEI, METC

Market Movers | Winners: CYPH, ABTC, MRLN | Losers: RARE, MEI, METC

September 4th, 2026 by Trefis Team
SPY
State Street SPDR S&P 500 ETF Trust

A quiet day for the averages hid some extreme moves for individual names.

Ultragenyx Pharmaceutical (RARE) ended the day down 44.0% against a market that was broadly positive. The S&P 500 returned +1.1%, the Dow Jones Industrial Average returned +1.2%, and the Nasdaq-100 returned +1.2%.

How can such a steep decline happen on a day of uniform strength for the major indexes? The day's full list of winners and losers offers the first clues.

Photo by ArtsyBee on Pixabay

Thursday's Market Winners

The 10 stocks with the highest returns on the last trading day:

# Ticker Company Name 1-D
Returns
YTD
Returns
1 CYPH Cypherpunk Technologies 35.1% 95.7%
2 ABTC American Bitcoin 18.7% -63.4%
3 MRLN Merlin 17.9% n/a
4 MSTR Strategy 17.6% -4.7%
5 SMMT Summit Therapeutics 17.3% -2.1%
6 HOOD Robinhood Markets 16.6% 10.3%
7 SNOW Snowflake 16.6% 62.5%
8 CRCL Circle Internet 16.5% 30.2%
9 ORBS Eightco 15.8% -43.9%
10 BMNR BitMine Immersion Technologies 14.7% -2.6%

Thursday's Market Losers

And the 10 stocks with the lowest returns:

# Ticker Company Name 1-D
Returns
YTD
Returns
1 RARE Ultragenyx Pharmaceutical -44.0% -35.4%
2 MEI Methode Electronics -15.4% 134.7%
3 METC Ramaco Resources -14.3% -31.4%
4 VSXY Victoria's Secret -13.2% 35.9%
5 IMUX Immunic -10.4% 139.1%
6 CIEN Ciena -10.4% 35.7%
7 CXM Sprinklr -10.2% -19.8%
8 BTQ BTQ Technologies -8.9% -41.8%
9 PL Planet Labs PBC -8.2% -6.9%
10 SION Sionna Therapeutics -7.7% -83.6%

Is today's biggest winner a flash in the pan?

Cypherpunk Technologies (CYPH) was the strongest stock of the day, returning +35.1%. But this move shows persistence. The stock also appears on the one-month winners list with a total return of +209.7%.

Its strength is not a one-day event; excluding today, the stock still gained +129.2% over the other sessions. For context, its market value is about $418.4 million.

Movers Over The Last Week

Widening the window to five trading days, these are the strongest and weakest Market names:

# Ticker Company Name 1-W
Returns
YTD
Returns
1 MNTK Montauk Renewables 25.0% 34.7%
2 TITN Titan Machinery 23.9% 51.8%
3 MMED Minimed 22.2% n/a
4 FMC FMC Corp 21.8% -5.3%
5 CNH CNH Industrial 21.1% 51.6%
6 CYPH Cypherpunk Technologies 20.1% 95.7%
7 SMMT Summit Therapeutics 19.5% -2.1%
8 IRD Opus Genetics 19.5% 128.9%
9 LMB Limbach 18.7% -36.4%
10 ORBS Eightco 18.2% -43.9%
# Ticker Company Name 1-W
Returns
YTD
Returns
1 ALMS Alumis -51.1% 16.4%
2 RARE Ultragenyx Pharmaceutical -43.5% -35.4%
3 CRDO Credo Technology -31.7% 14.1%
4 LPTH LightPath Technologies -30.1% -10.7%
5 FCEL FuelCell Energy -24.1% 100.7%
6 EIX Edison International -23.6% -2.5%
7 TRON TRON Inc -23.4% 32.3%
8 PCG PG&E -22.2% -12.6%
9 ENOV Enovis -21.9% -27.2%
10 IMUX Immunic -21.7% 139.1%

Movers Over The Last Month

And over the last 21 trading days:

# Ticker Company Name 1-M
Returns
YTD
Returns
1 CYPH Cypherpunk Technologies 209.7% 95.7%
2 MRNA Moderna 164.6% 404.8%
3 ARCT Arcturus Therapeutics 148.6% 153.8%
4 RCEL AVITA Medical 144.7% 217.1%
5 CAPR Capricor Therapeutics 136.1% -67.8%
6 OABI OmniAb 134.0% 156.8%
7 QMCO Quantum 109.8% 276.7%
8 IOVA Iovance Biotherapeutics 100.5% 218.7%
9 ABCL AbCellera Biologics 95.4% 238.3%
10 SENS Senseonics 91.1% 79.3%
# Ticker Company Name 1-M
Returns
YTD
Returns
1 SION Sionna Therapeutics -85.7% -83.6%
2 EYPT EyePoint -62.7% -75.0%
3 ALMS Alumis -58.1% 16.4%
4 TDUP ThredUp -57.5% -58.2%
5 KLC KinderCare Learning Companies -49.1% -37.7%
6 UTI Universal Technical Institute -49.0% -17.3%
7 LASR nLight -44.9% 10.6%
8 CDNL Cardinal Infrastructure -44.1% 46.2%
9 PLTK Playtika -42.4% -43.3%
10 AADX Applied Aerospace & Defense -41.0% n/a

A movers list is a map of attention, not a set of instructions.

The tables above show where capital and risk were most concentrated over three different time horizons. A large, sudden move is simply information, highlighting a stock where the market's view may be changing quickly.

The disciplined next step is to investigate the business behind the price. The day's biggest loser, Ultragenyx Pharmaceutical (RARE), saw its revenue grow 17.5% over the last twelve months. That single fact complicates the story told by one day's trading.

The next step is never to trade the list; it is to test it. Our Guidance Momentum screen shows which risers have management raising guidance behind them, and our Buy the Dip screen shows which of the fallers still generate the growth and cash that make a recovery plausible.

Today's Winner Is Tomorrow's Loser Often Enough

The movers list is the most honest picture of single-stock risk the market prints each day: the same volatility that makes the winners column also fills the losers column, and no one reliably knows which side a stock lands on next.

That is the case for owning a disciplined basket instead of chasing the tape. The Trefis High Quality (HQ) Portfolio holds roughly 30 businesses selected for consistent cash generation, strong margins, and resilient balance sheets, sized and rebalanced with rules. It has a track record of outpacing a benchmark that combines the three major indices - the S&P 500, S&P Mid-cap, and Russell 2000. Watch the movers for information; let the portfolio do the compounding.

Insight Guru Inc. published this content on September 04, 2026, and is solely responsible for the information contained herein. Distributed via Public Technologies (PUBT), unedited and unaltered, on September 04, 2026 at 10:22 UTC. If you believe the information included in the content is inaccurate or outdated and requires editing or removal, please contact us at [email protected]