European Parliament

04/25/2025 | Press release | Archived content

Liver damage as a side effect of COVID-19 vaccination

Liver damage as a side effect of COVID-19 vaccination

25.4.2025

Question for written answer E-001675/2025
to the Commission
Rule 144
Gerald Hauser (PfE)

Scientific publications document cases of liver damage following vaccination against COVID-19, including immune-mediated hepatitis, acute liver cell injury and liver impairment in transplant patients. Here are a few examples:

- Liver injury following SARS-CoV-2 vaccination: A multicenter case series[1]

- Liver injury after SARS-CoV-2 vaccination: Features of immune-mediated hepatitis, role of corticosteroid therapy and outcome[2]

- Histological and serological features of acute liver injury after SARS-CoV-2 vaccination[3]

- Risk of acute liver injury following the mRNA (BNT162b2) and inactivated (CoronaVac) COVID-19 vaccines[4]

- Severe de novo liver injury after Moderna vaccination - not always autoimmune hepatitis[5]

Not only can liver damage be caused by mRNA vaccination, but the vaccines also have a wide range of other side effects.

  • 1.In hindsight, what does the Commission make of the scientific diligence shown in authorising the mRNA vaccines in view of the wide range of side effects they have?
  • 2.Are any investigations currently being carried out by the Commission or subordinate EU authorities into the safety of mRNA vaccines?
  • 3.Were potential hepatotoxicity, genotoxicity, cardiotoxic effects, immunotoxicity, neurotoxic effects and possible long-term effects on liver function and genetic integrity investigated when the mRNA vaccines were authorised?

Submitted: 25.4.2025

  • [1] https://pubmed.ncbi.nlm.nih.gov/34339763/
  • [2] https://pubmed.ncbi.nlm.nih.gov/35567545/
  • [3] https://pubmed.ncbi.nlm.nih.gov/36440259/
  • [4] https://pubmed.ncbi.nlm.nih.gov/35817224/
  • [5] https://pubmed.ncbi.nlm.nih.gov/35439566/
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